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Exposure to Atrazine by Drinking Water and the Increased Risk of Neonatal Complications in Consequence: A Meta-Analysis Publisher Pubmed



Ghorbani Nejad B1 ; Rahimi Kakavandi N2 ; Mirzaei S3 ; Rastegar Pouyani N4 ; Habibian Sezavar A4
Authors
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Authors Affiliations
  1. 1. Department of Toxicology and Pharmacology, Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran
  2. 2. Department of Occupational Health Engineering, School of Health, Ilam University of Medical Sciences, Ilam, Iran
  3. 3. Department of Plant Protection, Faculty of Agriculture, Bu-Ali Sina University, Hamedan, Iran
  4. 4. Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences (TUMS), Tehran, Iran

Source: International Journal of Environmental Health Research Published:2024


Abstract

This meta-analysis evaluates the association between atrazine (ATR) exposure and small for gestational age (SGA), preterm birth (PTB), and low birth weight (LBW). A comprehensive search was done on academic databases (e.g. PubMed, Scopus, Embase, and Google Scholar) to achieve all pertinent studies up to May 2023. A pooled odd ratio (OR) and corresponding 95% confidence interval (CI) were applied to evaluate this correlation. As a result, five eligible studies met the inclusion criteria and were included in our study, and the result of the present meta-analysis showed that ATR exposure increased the risk of SGA (OR = 1.11; 95% CI = 1.03–1.20 for highest versus lowest category of ATR), PTB (OR = 1.16; 95% CI = 1.03–1.30), and LBW (OR = 1.26; 95% CI = 1.10–1.44). This meta-analysis suggests that ATR in drinking water may be a risk factor for SGA, PTB, and LBW. © 2023 Informa UK Limited, trading as Taylor & Francis Group.
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