Effects of Smoking on Covid-19 Management and Mortality: An Umbrella Review Publisher



Seyedalinaghi S¹ ; Afsahi AM² ; Shahidi R³ ; Kianzad S⁴ ; Pashaei Z¹ ; Mirahmad M⁵ ; Asili P⁶ ; Mojdeganlou H⁷ ; Razi A⁸ ; Mojdeganlou P⁹ ; Fard IA¹⁰ ; Mahdiabadi S⁸ ; Afzalian A⁸ ; Dashti M¹¹ Show All Authors Show Affiliations
Source: Journal of Smoking Cessation Published:2023

Abstract

Introduction. Smoking status appears to lead to a poor prognosis in COVID-19 patients. However, findings from the studies conducted on this topic have not been consistent, and further exploration is required. Methods. The objective of this umbrella review was to examine the effects of smoking on COVID-19 management and mortality. Online databases that included PubMed, Embase, Scopus, and Web of Science were searched using relevant keywords up to July 27, 2022. Articles were restricted to the English language, and the PRISMA protocol was followed. Results. A total of 27 systematic reviews, published from 2020 to 2022, were included. Individual studies included in the systematic reviews ranged from 8 to 186, with various population sizes. The consensus from the majority of systematic reviews was that COVID-19 smoker patients experience greater disease severity, disease progression, hospitalization rate, hospital admission duration, mechanical ventilation, ICU admission, and mortality rate. Conclusions. COVID-19 patients with a history of smoking (current and former) are vulnerable to adverse hospital outcomes and worse COVID-19 progression. Effective preventive and supportive approaches are required to decrease the risk of COVID-19 morbidity and mortality in patients with a history of smoking. © 2023 SeyedAhmad SeyedAlinaghi et al.