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The Association of Iron Intake and Hypertension, Does Iron Intake Decrease Blood Pressure? Publisher Pubmed



Mousavi Mele M1 ; Tahavorgar A2 ; Salimi Z3 ; Shaker A4 ; Askarpour SA5 ; Mohammadian MK6 ; Mirshafaei SR7 ; Saeedirad Z9 ; Torkaman M10 ; Mahmoudi Z6 ; Tajadod S11 ; Khoshdooz S12 ; Doaei S13 ; Kooshki A14 Show All Authors
Authors
  1. Mousavi Mele M1
  2. Tahavorgar A2
  3. Salimi Z3
  4. Shaker A4
  5. Askarpour SA5
  6. Mohammadian MK6
  7. Mirshafaei SR7
  8. Saeedirad Z9
  9. Torkaman M10
  10. Mahmoudi Z6
  11. Tajadod S11
  12. Khoshdooz S12
  13. Doaei S13
  14. Kooshki A14
  15. Gholamalizadeh M16
Show Affiliations
Authors Affiliations
  1. 1. Department of Nutrition, School of Public Health, International Campus, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  4. 4. Cellular and Molecular Biology, Islamic Azad University of Mashhad, Mashhad, Iran
  5. 5. Division of Food Safety and Hygiene, Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran
  7. 7. Department of Applied Mathematics, Faculty of Mathematical Sciences, Roudsar & amp
  8. 8. Amlash Branch, Islamic Azad University, Roudsar, Iran
  9. 9. Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  10. 10. Department of Chemical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran
  11. 11. Department of nutrition, School of Public health, International campus, Iran University of Medical Sciences, International Campus, Tehran, Iran
  12. 12. Guilan University of Medical Sciences, Rasht, Iran
  13. 13. Department of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  14. 14. Non-Communicable Diseases Research Center, Department of Nutrition & amp
  15. 15. Biochemistry, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran
  16. 16. Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Cardiovascular Toxicology Published:2024


Abstract

Previous studies reported that iron may have an indispensable role in the risk of hypertension (HTN). However, the result of the studies on the relationship between iron and risk of HTN is inconsistent. This study aimed to assess the association between the association of dietary iron intake and HTN in the Iranian population. This case–control study was conducted on 4184 people aged 35 to 70, including 1239 people with HTN and 2945 people with normal blood pressure (BP) in Sabzevar, Iran. Dietary intake was assessed using a food frequency questionnaire (FFQ). The Nutritionist IV software was used in terms of the assessment of dietary intake of iron. An inverse association was found between iron intake and HTN (OR = 0.97, CI 95%: 0.94–0.99, P = 0.04). The association remained significant after adjustment for age, gender, smoking, drinking alcohol, calorie intake, and BMI (OR = 0.94, CI 95%: 0.89–0.98, P = 0.01). As a conclusion, iron intake was inversely associated with HTN. Further longitudinal studies on the effect of iron intake on BP are required to confirm this finding. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.
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