The Association of Iron Intake and Hypertension, Does Iron Intake Decrease Blood Pressure? Publisher Pubmed



Mousavi Mele M¹ ; Tahavorgar A² ; Salimi Z³ ; Shaker A⁴ ; Askarpour SA⁵ ; Mohammadian MK⁶ ; Mirshafaei SR⁷ ; Saeedirad Z⁹ ; Torkaman M¹⁰ ; Mahmoudi Z⁶ ; Tajadod S¹¹ ; Khoshdooz S¹² ; Doaei S¹³ ; Kooshki A¹⁴ Show All Authors
Source: Cardiovascular Toxicology Published:2024

Abstract

Previous studies reported that iron may have an indispensable role in the risk of hypertension (HTN). However, the result of the studies on the relationship between iron and risk of HTN is inconsistent. This study aimed to assess the association between the association of dietary iron intake and HTN in the Iranian population. This case–control study was conducted on 4184 people aged 35 to 70, including 1239 people with HTN and 2945 people with normal blood pressure (BP) in Sabzevar, Iran. Dietary intake was assessed using a food frequency questionnaire (FFQ). The Nutritionist IV software was used in terms of the assessment of dietary intake of iron. An inverse association was found between iron intake and HTN (OR = 0.97, CI 95%: 0.94–0.99, P = 0.04). The association remained significant after adjustment for age, gender, smoking, drinking alcohol, calorie intake, and BMI (OR = 0.94, CI 95%: 0.89–0.98, P = 0.01). As a conclusion, iron intake was inversely associated with HTN. Further longitudinal studies on the effect of iron intake on BP are required to confirm this finding. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.