Liver-On-A-Chip

Liver-On-A-Chip Publisher

Mirzababaei S¹ ; Navaeinigjeh M^{1, 2} ; Abdollahi M¹ ; Shamloo A³

Show Affiliations

1. Pharmaceutical Sciences Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences (TUMS), Tehran, Iran
2. Department of Pharmaceutical Biomaterials, Medical Biomaterials Research Centre, Faculty of Pharmacy, Tehran University of Medical Sciences (TUMS), Tehran, Iran
3. Department of Mechanical Engineering, Sharif University of Technology, Tehran, Iran

Source: Principles of Human Organs-on-Chips Published:2023

Abstract

The liver is the most metabolically active organ in the human body whose role is of high importance to maintain homeostasis. Drug-induced liver injury and liver diseases such as fatty liver diseases, cancer, or hepatitis are the main reasons for malfunctioning in this organ. In this regard, developing physiologically relevant models could be remarkably useful both for the pharmaceutical industry and the study of (patho)physiology of the liver. Among different in vitro cell cultures, organ-on-a-chip (OOC) could be a promising candidate for liver studies. Liver-on-a-chip (LOC) models propose high-fidelity in vitro models by incorporating perfusion, different cell types, and 3D environment. Therefore, they could be used to model (patho)physiological state of the liver to propose new treatments for liver diseases and toxicity essays. In addition, the integration of LOC with other OOCs could be useful to study the intercommunication of the liver with other organs. © 2023 Elsevier Ltd. All rights reserved.

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Style	Citing Format
MLA	Mirzababaei S, et al.. "Liver-On-A-Chip." Principles of Human Organs-on-Chips, vol. , no. , 2023, pp. 195-249.
APA	Mirzababaei S, Navaeinigjeh M, Abdollahi M, Shamloo A (2023). Liver-On-A-Chip. Principles of Human Organs-on-Chips, (), 195-249.
Chicago	Mirzababaei S, Navaeinigjeh M, Abdollahi M, Shamloo A. "Liver-On-A-Chip." Principles of Human Organs-on-Chips , no. (2023): 195-249.
Harvard	Mirzababaei S et al. (2023) 'Liver-On-A-Chip', Principles of Human Organs-on-Chips, (), pp. 195-249.
Vancouver	Mirzababaei S, Navaeinigjeh M, Abdollahi M, Shamloo A. Liver-On-A-Chip. Principles of Human Organs-on-Chips. 2023;():195-249.
BibTex	@article{ author = {Mirzababaei S and Navaeinigjeh M and Abdollahi M and Shamloo A}, title = {Liver-On-A-Chip}, journal = {Principles of Human Organs-on-Chips}, volume = {}, number = {}, pages = {195-249}, year = {2023} }
RIS	TY - JOUR AU - Mirzababaei S AU - Navaeinigjeh M AU - Abdollahi M AU - Shamloo A TI - Liver-On-A-Chip JO - Principles of Human Organs-on-Chips VL - IS - SP - 195 EP - 249 PY - 2023 ER -

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