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Nanotechnology-Assisted Microfluidic Systems: From Bench to Bedside Publisher Pubmed



Rabiee N1 ; Ahmadi S2, 3 ; Fatahi Y4, 5 ; Rabiee M6 ; Bagherzadeh M1 ; Dinarvand R4, 5 ; Bagheri B7 ; Zarrintaj P8 ; Saeb MR9 ; Webster TJ10
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Chemistry, Sharif University of Technology, Tehran, Iran
  2. 2. Student Research Committee, Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Cellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Department of Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Nanotechnology Research Centre, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Biomaterial Group, Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran
  7. 7. Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, South Korea
  8. 8. School of Chemical Engineering, Oklahoma State University, 420 Engineering North, Stillwater, 74078, OK, United States
  9. 9. Universite de Lorraine, INRAE, LERMAB, Nancy, F-54000, France
  10. 10. Department of Chemical Engineering, Northeastern University, Boston, 02115, MA, United States

Source: Nanomedicine Published:2021


Abstract

With significant advancements in research technologies, and an increasing global population, microfluidic and nanofluidic systems (such as point-of-care, lab-on-a-chip, organ-on-a-chip, etc) have started to revolutionize medicine. Devices that combine micron and nanotechnologies have increased sensitivity, precision and versatility for numerous medical applications. However, while there has been extensive research on microfluidic and nanofluidic systems, very few have experienced wide-spread commercialization which is puzzling and deserves our collective attention. For the above reasons, in this article, we review research advances that combine micro and nanotechnologies to create the next generation of nanomaterial-based microfluidic systems, the latest in their commercialization success and failure and highlight the value of these devices both in industry and in the laboratory. © 2021 Future Medicine Ltd.
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