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Comparison of Decision-Making Processes Between Subjects With a Positive and Negative History of Substance Use Publisher



Sisakht RR1 ; Negarandeh R2 ; Valizadegan H3 ; Mousavi S4 ; Noroozian M5 ; Tehranidoost M1, 6 ; Razaghi E7, 8
Authors
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Authors Affiliations
  1. 1. Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Medecins Sans Frontieres (MSF), Southern Tehran Project, Tehran, Iran
  3. 3. Behsazan Mellat Co., Tehran, Iran
  4. 4. Max Planck Institute for Human Development, Berlin, Germany
  5. 5. Memory and Behavioral Neurology Division, Department of Psychiatry, Ruzbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Psychiatry, Research Center for Cognitive and Behavioral Studies, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. School of Advanced Technologies, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Department of Psychiatry, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Psychiatry and Behavioral Sciences Published:2019


Abstract

Background: Studies related to decision-making and choice preference in substance use behavior have less commonly focused on decision-making processes per se. Those processes include decision-making time, task-based complexity, and decision-making strategies. Objectives: The objectives of this studywasthe production of a culturallymodifiedversion of the Mouselab tool formeasurementof decision-making processes and to measure differences between decision-making processes in subjects with a positive and negative history of substance use. Methods: Applying a snowball method for sampling, two groups, of individuals with a positive and negative history of substance use were recruited. The case and control groups consisted of 17 males with the mean age of 35.94 (± 12) and 33.8 (± 8.83) years, respectively. The measurement tool was a modified version of Mouselab computer game. Results: Using repeated measurement analysis of variances ant t-test with non-paired groups for comparing the case and control groups, it was found that the group with a positive history of substance use had a longer time-lapse in the decision-making process (P = 0.029). The accuracy of choice, however, was not different between the groups (P = 0.172). Conclusions: Subjects with a positive history of substance use were different in two stages of decision-making process, which are dependent on the ecology and conditions of decision-making process, namely, search for information and decision-making. Two other stages of decision-making process that were dependent on individual cognitive and logical properties, i.e., stop search and choice, were not different in subjects with a positive history of substance use compared to the control group. Although subjects with a positive history of substance use consumed more resources for decision-making, their accuracy of choice was not different from the control group, thereby, ruling out a decision-making-related cognitive deficit. © 2019, Author(s).