Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?

Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease? Publisher Pubmed

Sanchoshimizu V^{1, 2} ; Brodin P³ ; Cobat A^{4, 5, 6, 83} ; Biggs CM^{7, 8} ; Toubiana J^{9, 10} ; Lucas CL¹¹ ; Henrickson SE^{12, 13} ; Belot A^{14, 15} ; Tangye SG^{16, 17} ; Milner JD¹⁸ ; Levin M^{1, 2} ; Abel L^{4, 5, 6, 83} ; Bogunovic D¹⁹ ; Casanova JL^{4, 5, 6, 20, 83} Show All Authors

Sanchoshimizu V^{1, 2}
Brodin P³
Cobat A^{4, 5, 6, 83}
Biggs CM^{7, 8}
Toubiana J^{9, 10}
Lucas CL¹¹
Henrickson SE^{12, 13}
Belot A^{14, 15}
Tangye SG^{16, 17}
Milner JD¹⁸
Levin M^{1, 2}
Abel L^{4, 5, 6, 83}
Bogunovic D¹⁹
Casanova JL^{4, 5, 6, 20, 83}
Zhang SY^{4, 5, 6, 83}
Haddad E²¹
Beland K²¹
Pujol A^{22, 23, 24}
Schluter A²²
Planasserra L²²
Aguileraalbesa S²⁵
Valenciaramos J²⁶
Rodriguezpalmero A²⁷
Gut M²⁸
Riviere JG²⁹
Colobran R³⁰
Solerpalacin P²⁹
Rodriguezgallego C^{31, 32}
De Diego RP^{33, 34}
Flores C^{35, 36, 37, 38}
Alsina L³⁹
Blazquezgamero D⁴⁰
Jordan I⁴¹
Keles S⁴²
Emiroglu M⁴³
Akcan OM⁴²
Alkan G⁴⁴
Aytekin SE⁴²
Gul Y⁴²
Tuter Oz SK⁴⁴
Bozdemir SE⁴⁵
Bayhan GI⁴⁶
Yuksek SK⁴⁷
Parlakay AO⁴⁶
Gulhan B⁴⁷
Yahsi A⁴⁷
Kilic AO⁴²
Karbuz A⁴⁸
Erdeniz EH⁴⁹
Ozkan EA⁴⁹
Orbak Z⁵⁰
Aydemir S⁵¹
Celik JB⁴⁴
Kandemir B⁴²
Aytekin G⁵²
Kapakli H⁵³
Yarar V⁵³
Yosunkaya A⁴²
Vatansev H⁴²
Aytekin C⁵⁴
Torun SH⁵⁵
Nepesov S⁵⁶
Coskuner T⁵⁷
Sozeri B⁵⁷
Demirkol YK⁵⁸
Kasapcopur O⁵⁹
Yildiz M⁵⁹
Sevketoglu E⁶⁰
Hatipoglu N⁶¹
Ozcelik T⁶²
Yesilbas O⁶³
Gayretli Aydin ZG⁶⁴
Sediva A⁶⁵
Klocperk A⁶⁵
Bloomfield M^{65, 66}
Meyts I⁶⁷
Delafontaine S⁶⁷
Haerynck F⁶⁸
Hoste L⁶⁸
Shahrooei M⁶⁹
Marque L⁷⁰
Neves JF^{71, 72}
Novelli G⁷³
Novelli A⁷⁴
Aiuti A⁷⁵
Casari G⁷⁵
Bousfiha AA⁷⁶
Almuhsen SZ⁷⁷
Sobh A⁷⁸
Gagro A^{79, 80}
Bajolle F⁸¹
Bonnet D⁸¹
Lebon P⁸²
Lei W^{4, 83}
Lee D^{4, 83}
Seeleuthner Y^{84, 85}
Zhang P^{4, 83}
Maglorius M^{84, 85}
Philippot Q^{84, 85}
Pelham S^{4, 83}
Bastard P^{84, 85}
Zhang Q^{4, 83}
Jouanguy E^{84, 85}
Puel A^{84, 85}
Herberg J⁸⁶
Kuijpers TW^{87, 88}
Bellos E⁸⁶
Kaforou M⁸⁶
Menikou S⁸⁶
Panhammarstrom Q⁸⁹
Hammarstrom L⁹⁰
Abolhassani H⁸⁹
Bryceson Y⁹¹
Condinoneto A⁹²
Prando C⁹³
Bando SY⁹⁴
Cavalcanti A⁹⁵
Fellay J^{96, 97}
Blanchardhohner G⁹⁸
Mansouri D⁹⁹
Mahmoudi S¹⁰⁰
Boyarchuk O¹⁰¹
Volokha A¹⁰²
Bondarenko A¹⁰³
Stepanovskiy Y¹⁰³
Mogensen T¹⁰⁴
Van De Beek D¹⁰⁵
Andreakos E¹⁰⁶
Papadaki M¹⁰⁶
Tayoun AA^{107, 108}
Halwani R¹⁰⁹
Almulla F¹¹⁰
Franco JL¹¹¹
Lau YL¹¹²
Kwan M¹¹³
Imai K¹¹⁴
Okada S¹¹⁵
Bolze A¹¹⁶
Butte MJ¹¹⁷
Hsieh E¹¹⁸
Drolet BA¹¹⁹
Arkin L¹¹⁹
Itan Y¹²⁰
Maniatis T¹²¹
Arditi M¹²²
Cooper M¹²³
Schmitt E¹²³
Chakravorty S¹²⁴
Anderson MS¹²⁵
Su HC¹²⁶
Notarangelo LD¹²⁶

Source: Journal of Experimental Medicine Published:2021

Abstract

Multisystem inflammatory syndrome in children (MIS-C) emerged in April 2020 in communities with high COVID-19 rates. This new condition is heterogenous but resembles Kawasaki disease (KD), a well-known but poorly understood and clinically heterogenous pediatric inflammatory condition for which weak associations have been found with a myriad of viral illnesses. Epidemiological data clearly indicate that SARS-CoV-2 is the trigger for MIS-C, which typically occurs about 1 mo after infection. These findings support the hypothesis of viral triggers for the various forms of classic KD. We further suggest that rare inborn errors of immunity (IEIs) altering the immune response to SARS-CoV-2 may underlie the pathogenesis of MIS-C in some children. The discovery of monogenic IEIs underlying MIS-C would shed light on its pathogenesis, paving the way for a new genetic approach to classic KD, revisited as a heterogeneous collection of IEIs to viruses. © 2021 Sancho-Shimizu et al.

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Style	Citing Format
MLA	Sanchoshimizu V, et al.. "Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?." Journal of Experimental Medicine, vol. 218, no. 6, 2021, pp. -.
APA	Sanchoshimizu V, Brodin P, Cobat A, Biggs CM, Toubiana J, Lucas CL, Henrickson SE, Belot A, Tangye SG, Milner JD, Levin M, Abel L, Bogunovic D, Casanova JL, Zhang SY, Haddad E, Beland K, Pujol A, Schluter A, ... Notarangelo LD (2021). Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?. Journal of Experimental Medicine, 218(6), -.
Chicago	Sanchoshimizu V, Brodin P, Cobat A, Biggs CM, Toubiana J, Lucas CL, Henrickson SE, et al.. "Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?." Journal of Experimental Medicine 218, no. 6 (2021): -.
Harvard	Sanchoshimizu V et al. (2021) 'Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?', Journal of Experimental Medicine, 218(6), pp. -.
Vancouver	Sanchoshimizu V, Brodin P, Cobat A, Biggs CM, Toubiana J, Lucas CL, et al.. Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?. Journal of Experimental Medicine. 2021;218(6):-.
BibTex	@article{ author = {Sanchoshimizu V and Brodin P and Cobat A and Biggs CM and Toubiana J and Lucas CL and Henrickson SE and Belot A and Tangye SG and Milner JD and Levin M and Abel L and Bogunovic D and Casanova JL and Zhang SY and Haddad E and Beland K and Pujol A and Schluter A and Planasserra L and Aguileraalbesa S and Valenciaramos J and Rodriguezpalmero A and Gut M and Riviere JG and Colobran R and Solerpalacin P and Rodriguezgallego C and De Diego RP and Flores C and Alsina L and Blazquezgamero D and Jordan I and Keles S and Emiroglu M and Akcan OM and Alkan G and Aytekin SE and Gul Y and Tuter Oz SK and Bozdemir SE and Bayhan GI and Yuksek SK and Parlakay AO and Gulhan B and Yahsi A and Kilic AO and Karbuz A and Erdeniz EH and Ozkan EA and Orbak Z and Aydemir S and Celik JB and Kandemir B and Aytekin G and Kapakli H and Yarar V and Yosunkaya A and Vatansev H and Aytekin C and Torun SH and Nepesov S and Coskuner T and Sozeri B and Demirkol YK and Kasapcopur O and Yildiz M and Sevketoglu E and Hatipoglu N and Ozcelik T and Yesilbas O and Gayretli Aydin ZG and Sediva A and Klocperk A and Bloomfield M and Meyts I and Delafontaine S and Haerynck F and Hoste L and Shahrooei M and Marque L and Neves JF and Novelli G and Novelli A and Aiuti A and Casari G and Bousfiha AA and Almuhsen SZ and Sobh A and Gagro A and Bajolle F and Bonnet D and Lebon P and Lei W and Lee D and Seeleuthner Y and Zhang P and Maglorius M and Philippot Q and Pelham S and Bastard P and Zhang Q and Jouanguy E and Puel A and Herberg J and Kuijpers TW and Bellos E and Kaforou M and Menikou S and Panhammarstrom Q and Hammarstrom L and Abolhassani H and Bryceson Y and Condinoneto A and Prando C and Bando SY and Cavalcanti A and Fellay J and Blanchardhohner G and Mansouri D and Mahmoudi S and Boyarchuk O and Volokha A and Bondarenko A and Stepanovskiy Y and Mogensen T and Van De Beek D and Andreakos E and Papadaki M and Tayoun AA and Halwani R and Almulla F and Franco JL and Lau YL and Kwan M and Imai K and Okada S and Bolze A and Butte MJ and Hsieh E and Drolet BA and Arkin L and Itan Y and Maniatis T and Arditi M and Cooper M and Schmitt E and Chakravorty S and Anderson MS and Su HC and Notarangelo LD}, title = {Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?}, journal = {Journal of Experimental Medicine}, volume = {218}, number = {6}, pages = {-}, year = {2021} }
RIS	TY - JOUR AU - Sanchoshimizu V AU - Brodin P AU - Cobat A AU - Biggs CM AU - Toubiana J AU - Lucas CL AU - Henrickson SE AU - Belot A AU - Tangye SG AU - Milner JD AU - Levin M AU - Abel L AU - Bogunovic D AU - Casanova JL AU - Zhang SY AU - Haddad E AU - Beland K AU - Pujol A AU - Schluter A AU - Planasserra L AU - Aguileraalbesa S AU - Valenciaramos J AU - Rodriguezpalmero A AU - Gut M AU - Riviere JG AU - Colobran R AU - Solerpalacin P AU - Rodriguezgallego C AU - De Diego RP AU - Flores C AU - Alsina L AU - Blazquezgamero D AU - Jordan I AU - Keles S AU - Emiroglu M AU - Akcan OM AU - Alkan G AU - Aytekin SE AU - Gul Y AU - Tuter Oz SK AU - Bozdemir SE AU - Bayhan GI AU - Yuksek SK AU - Parlakay AO AU - Gulhan B AU - Yahsi A AU - Kilic AO AU - Karbuz A AU - Erdeniz EH AU - Ozkan EA AU - Orbak Z AU - Aydemir S AU - Celik JB AU - Kandemir B AU - Aytekin G AU - Kapakli H AU - Yarar V AU - Yosunkaya A AU - Vatansev H AU - Aytekin C AU - Torun SH AU - Nepesov S AU - Coskuner T AU - Sozeri B AU - Demirkol YK AU - Kasapcopur O AU - Yildiz M AU - Sevketoglu E AU - Hatipoglu N AU - Ozcelik T AU - Yesilbas O AU - Gayretli Aydin ZG AU - Sediva A AU - Klocperk A AU - Bloomfield M AU - Meyts I AU - Delafontaine S AU - Haerynck F AU - Hoste L AU - Shahrooei M AU - Marque L AU - Neves JF AU - Novelli G AU - Novelli A AU - Aiuti A AU - Casari G AU - Bousfiha AA AU - Almuhsen SZ AU - Sobh A AU - Gagro A AU - Bajolle F AU - Bonnet D AU - Lebon P AU - Lei W AU - Lee D AU - Seeleuthner Y AU - Zhang P AU - Maglorius M AU - Philippot Q AU - Pelham S AU - Bastard P AU - Zhang Q AU - Jouanguy E AU - Puel A AU - Herberg J AU - Kuijpers TW AU - Bellos E AU - Kaforou M AU - Menikou S AU - Panhammarstrom Q AU - Hammarstrom L AU - Abolhassani H AU - Bryceson Y AU - Condinoneto A AU - Prando C AU - Bando SY AU - Cavalcanti A AU - Fellay J AU - Blanchardhohner G AU - Mansouri D AU - Mahmoudi S AU - Boyarchuk O AU - Volokha A AU - Bondarenko A AU - Stepanovskiy Y AU - Mogensen T AU - Van De Beek D AU - Andreakos E AU - Papadaki M AU - Tayoun AA AU - Halwani R AU - Almulla F AU - Franco JL AU - Lau YL AU - Kwan M AU - Imai K AU - Okada S AU - Bolze A AU - Butte MJ AU - Hsieh E AU - Drolet BA AU - Arkin L AU - Itan Y AU - Maniatis T AU - Arditi M AU - Cooper M AU - Schmitt E AU - Chakravorty S AU - Anderson MS AU - Su HC AU - Notarangelo LD TI - Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease? JO - Journal of Experimental Medicine VL - 218 IS - 6 SP - EP - PY - 2021 ER -

Style

Citing Format

MLA

Sanchoshimizu V, et al.. "Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?." Journal of Experimental Medicine, vol. 218, no. 6, 2021, pp. -.

APA

Sanchoshimizu V, Brodin P, Cobat A, Biggs CM, Toubiana J, Lucas CL, Henrickson SE, Belot A, Tangye SG, Milner JD, Levin M, Abel L, Bogunovic D, Casanova JL, Zhang SY, Haddad E, Beland K, Pujol A, Schluter A, ... Notarangelo LD (2021). Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?. Journal of Experimental Medicine, 218(6), -.

Chicago

Sanchoshimizu V, Brodin P, Cobat A, Biggs CM, Toubiana J, Lucas CL, Henrickson SE, et al.. "Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?." Journal of Experimental Medicine 218, no. 6 (2021): -.

Harvard

Sanchoshimizu V et al. (2021) 'Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?', Journal of Experimental Medicine, 218(6), pp. -.

Vancouver

Sanchoshimizu V, Brodin P, Cobat A, Biggs CM, Toubiana J, Lucas CL, et al.. Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?. Journal of Experimental Medicine. 2021;218(6):-.

BibTex

@article{ author = {Sanchoshimizu V and Brodin P and Cobat A and Biggs CM and Toubiana J and Lucas CL and Henrickson SE and Belot A and Tangye SG and Milner JD and Levin M and Abel L and Bogunovic D and Casanova JL and Zhang SY and Haddad E and Beland K and Pujol A and Schluter A and Planasserra L and Aguileraalbesa S and Valenciaramos J and Rodriguezpalmero A and Gut M and Riviere JG and Colobran R and Solerpalacin P and Rodriguezgallego C and De Diego RP and Flores C and Alsina L and Blazquezgamero D and Jordan I and Keles S and Emiroglu M and Akcan OM and Alkan G and Aytekin SE and Gul Y and Tuter Oz SK and Bozdemir SE and Bayhan GI and Yuksek SK and Parlakay AO and Gulhan B and Yahsi A and Kilic AO and Karbuz A and Erdeniz EH and Ozkan EA and Orbak Z and Aydemir S and Celik JB and Kandemir B and Aytekin G and Kapakli H and Yarar V and Yosunkaya A and Vatansev H and Aytekin C and Torun SH and Nepesov S and Coskuner T and Sozeri B and Demirkol YK and Kasapcopur O and Yildiz M and Sevketoglu E and Hatipoglu N and Ozcelik T and Yesilbas O and Gayretli Aydin ZG and Sediva A and Klocperk A and Bloomfield M and Meyts I and Delafontaine S and Haerynck F and Hoste L and Shahrooei M and Marque L and Neves JF and Novelli G and Novelli A and Aiuti A and Casari G and Bousfiha AA and Almuhsen SZ and Sobh A and Gagro A and Bajolle F and Bonnet D and Lebon P and Lei W and Lee D and Seeleuthner Y and Zhang P and Maglorius M and Philippot Q and Pelham S and Bastard P and Zhang Q and Jouanguy E and Puel A and Herberg J and Kuijpers TW and Bellos E and Kaforou M and Menikou S and Panhammarstrom Q and Hammarstrom L and Abolhassani H and Bryceson Y and Condinoneto A and Prando C and Bando SY and Cavalcanti A and Fellay J and Blanchardhohner G and Mansouri D and Mahmoudi S and Boyarchuk O and Volokha A and Bondarenko A and Stepanovskiy Y and Mogensen T and Van De Beek D and Andreakos E and Papadaki M and Tayoun AA and Halwani R and Almulla F and Franco JL and Lau YL and Kwan M and Imai K and Okada S and Bolze A and Butte MJ and Hsieh E and Drolet BA and Arkin L and Itan Y and Maniatis T and Arditi M and Cooper M and Schmitt E and Chakravorty S and Anderson MS and Su HC and Notarangelo LD}, title = {Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?}, journal = {Journal of Experimental Medicine}, volume = {218}, number = {6}, pages = {-}, year = {2021} }

RIS

TY - JOUR
AU - Sanchoshimizu V
AU - Brodin P
AU - Cobat A
AU - Biggs CM
AU - Toubiana J
AU - Lucas CL
AU - Henrickson SE
AU - Belot A
AU - Tangye SG
AU - Milner JD
AU - Levin M
AU - Abel L
AU - Bogunovic D
AU - Casanova JL
AU - Zhang SY
AU - Haddad E
AU - Beland K
AU - Pujol A
AU - Schluter A
AU - Planasserra L
AU - Aguileraalbesa S
AU - Valenciaramos J
AU - Rodriguezpalmero A
AU - Gut M
AU - Riviere JG
AU - Colobran R
AU - Solerpalacin P
AU - Rodriguezgallego C
AU - De Diego RP
AU - Flores C
AU - Alsina L
AU - Blazquezgamero D
AU - Jordan I
AU - Keles S
AU - Emiroglu M
AU - Akcan OM
AU - Alkan G
AU - Aytekin SE
AU - Gul Y
AU - Tuter Oz SK
AU - Bozdemir SE
AU - Bayhan GI
AU - Yuksek SK
AU - Parlakay AO
AU - Gulhan B
AU - Yahsi A
AU - Kilic AO
AU - Karbuz A
AU - Erdeniz EH
AU - Ozkan EA
AU - Orbak Z
AU - Aydemir S
AU - Celik JB
AU - Kandemir B
AU - Aytekin G
AU - Kapakli H
AU - Yarar V
AU - Yosunkaya A
AU - Vatansev H
AU - Aytekin C
AU - Torun SH
AU - Nepesov S
AU - Coskuner T
AU - Sozeri B
AU - Demirkol YK
AU - Kasapcopur O
AU - Yildiz M
AU - Sevketoglu E
AU - Hatipoglu N
AU - Ozcelik T
AU - Yesilbas O
AU - Gayretli Aydin ZG
AU - Sediva A
AU - Klocperk A
AU - Bloomfield M
AU - Meyts I
AU - Delafontaine S
AU - Haerynck F
AU - Hoste L
AU - Shahrooei M
AU - Marque L
AU - Neves JF
AU - Novelli G
AU - Novelli A
AU - Aiuti A
AU - Casari G
AU - Bousfiha AA
AU - Almuhsen SZ
AU - Sobh A
AU - Gagro A
AU - Bajolle F
AU - Bonnet D
AU - Lebon P
AU - Lei W
AU - Lee D
AU - Seeleuthner Y
AU - Zhang P
AU - Maglorius M
AU - Philippot Q
AU - Pelham S
AU - Bastard P
AU - Zhang Q
AU - Jouanguy E
AU - Puel A
AU - Herberg J
AU - Kuijpers TW
AU - Bellos E
AU - Kaforou M
AU - Menikou S
AU - Panhammarstrom Q
AU - Hammarstrom L
AU - Abolhassani H
AU - Bryceson Y
AU - Condinoneto A
AU - Prando C
AU - Bando SY
AU - Cavalcanti A
AU - Fellay J
AU - Blanchardhohner G
AU - Mansouri D
AU - Mahmoudi S
AU - Boyarchuk O
AU - Volokha A
AU - Bondarenko A
AU - Stepanovskiy Y
AU - Mogensen T
AU - Van De Beek D
AU - Andreakos E
AU - Papadaki M
AU - Tayoun AA
AU - Halwani R
AU - Almulla F
AU - Franco JL
AU - Lau YL
AU - Kwan M
AU - Imai K
AU - Okada S
AU - Bolze A
AU - Butte MJ
AU - Hsieh E
AU - Drolet BA
AU - Arkin L
AU - Itan Y
AU - Maniatis T
AU - Arditi M
AU - Cooper M
AU - Schmitt E
AU - Chakravorty S
AU - Anderson MS
AU - Su HC
AU - Notarangelo LD
TI - Sars-Cov-2-Related Mis-C: A Key to the Viral and Genetic Causes of Kawasaki Disease?
JO - Journal of Experimental Medicine
VL - 218
IS - 6
SP -
EP -
PY - 2021
ER -

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