Lessons From Ten Years’ the Prevalence of Congenital Rubella Syndrome (Crs) in the Young Population Living in a Developing Country, Tehran; Iran

Lessons From Ten Years’ the Prevalence of Congenital Rubella Syndrome (Crs) in the Young Population Living in a Developing Country, Tehran; Iran Publisher Pubmed

Noorbakhsh S¹ ; Vafaeeshahi M² ; Tahernia L³ ; Ashouri S⁴ ; Riahi A⁵

Show Affiliations

1. Pediatric Infectious Diseases, Departement & Research Center, Iran University of Medical Sciences, Tehran, Iran
2. Pediatrics Departement, Pediatric Growth and Development Research Center, Iran University of Medical Sciences, Tehran, Iran
3. Fellowship of Paediatric Intensive Care, Tehran University of Medical Sciences, Tehran, Iran
4. ENT and Head and Neck Research center and department, Iran University of medical sciences, Tehran, Iran
5. Pediatrician, Pediatrics Dep, Iran University of Medical Sciences, Tehran, Iran

Source: Infectious Disorders - Drug Targets Published:2022

Abstract

Background: A safe and effective rubella vaccine is available and prescribed in IRAN. Objective: This is a survey of CRS cases collected based on WHO criteria one decade after the MR vaccination campaign (2003) Methods: This Multi-stage prospective/cross-sectional study was carried out in three stages in 3 educational hospitals in Tehran (Rasoul Aram, Akbar Abadi, and Firoozabadi), In the first stage of the study between 2011 and 2012 total of 186 infants were evaluated, and in the second stage of the study, total 163 blood samples of infants with suspected INTRA UTERINE INFECTION were compared with a group of healthy matched infants. In the first and second stages, Rubella immunity (IgG&IgM) in cord blood was evaluated by the Eliza method. Results: Despite MR vaccination in Iran, after one decadeconfirmed CRS and compatible CRS was diagnosed in 5 and 31 from 89 CRS suspected cases. Conclusion: The incidence of confirmed CRS in every 100 CRS suspected infants (after campaign) is 5.6 %, and 31 CRS Compatible cases are so important. Without active CRS surveillance, mild infection such as IUGR, hearing loss, heart abnormalities, impaired vision, and mental retardation even in the developed country might be missed. Fetal infection is persistent, which imposes additional costs on the country. Another mass vaccination in women and girls is needed. Also, the anti-rubella IgG testing before pregnancy in women who were not vaccinated; vaccination of women before marriage/pregnancy should be obligatory in order to prevent the CRS. © 2022 Bentham Science Publishers.

Style	Citing Format
MLA	Noorbakhsh S, et al.. "Lessons From Ten Years’ the Prevalence of Congenital Rubella Syndrome (Crs) in the Young Population Living in a Developing Country, Tehran; Iran." Infectious Disorders - Drug Targets, vol. 22, no. 3, 2022, pp. -.
APA	Noorbakhsh S, Vafaeeshahi M, Tahernia L, Ashouri S, Riahi A (2022). Lessons From Ten Years’ the Prevalence of Congenital Rubella Syndrome (Crs) in the Young Population Living in a Developing Country, Tehran; Iran. Infectious Disorders - Drug Targets, 22(3), -.
Chicago	Noorbakhsh S, Vafaeeshahi M, Tahernia L, Ashouri S, Riahi A. "Lessons From Ten Years’ the Prevalence of Congenital Rubella Syndrome (Crs) in the Young Population Living in a Developing Country, Tehran; Iran." Infectious Disorders - Drug Targets 22, no. 3 (2022): -.
Harvard	Noorbakhsh S et al. (2022) 'Lessons From Ten Years’ the Prevalence of Congenital Rubella Syndrome (Crs) in the Young Population Living in a Developing Country, Tehran; Iran', Infectious Disorders - Drug Targets, 22(3), pp. -.
Vancouver	Noorbakhsh S, Vafaeeshahi M, Tahernia L, Ashouri S, Riahi A. Lessons From Ten Years’ the Prevalence of Congenital Rubella Syndrome (Crs) in the Young Population Living in a Developing Country, Tehran; Iran. Infectious Disorders - Drug Targets. 2022;22(3):-.
BibTex	@article{ author = {Noorbakhsh S and Vafaeeshahi M and Tahernia L and Ashouri S and Riahi A}, title = {Lessons From Ten Years’ the Prevalence of Congenital Rubella Syndrome (Crs) in the Young Population Living in a Developing Country, Tehran; Iran}, journal = {Infectious Disorders - Drug Targets}, volume = {22}, number = {3}, pages = {-}, year = {2022} }
RIS	TY - JOUR AU - Noorbakhsh S AU - Vafaeeshahi M AU - Tahernia L AU - Ashouri S AU - Riahi A TI - Lessons From Ten Years’ the Prevalence of Congenital Rubella Syndrome (Crs) in the Young Population Living in a Developing Country, Tehran; Iran JO - Infectious Disorders - Drug Targets VL - 22 IS - 3 SP - EP - PY - 2022 ER -

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