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Sero-Epidemiological Evaluation of Rubella Immunity Among Pre-Marriage Women in Iran Publisher Pubmed



Zahraei SM1 ; Mokhtariazad T2 ; Sabouri A1 ; Khazaei S3 ; Karami M4, 5
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Authors Affiliations
  1. 1. Center for Communicable Diseases Control, Ministry of Health and Medical Education, Tehran, Iran
  2. 2. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran
  4. 4. Social Determinants of Health Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
  5. 5. Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran

Source: Human Vaccines and Immunotherapeutics Published:2019


Abstract

Few studies have addressed the seroepidemiological profile of rubella among a representative population of young adult women. This study aims to determine the immunity and susceptibility rate against rubella in a representative population of women in reproductive age in Iran through serological evaluation. This cross-sectional study was conducted in 2012 on 804 pre-marriage women in Iran. Multi-stage random sampling was used for choosing study sample. Serologic test were used to assess subjects’ immunity to rubella and their titers of IgG antibody against rubella with ELISA method was measured. In total, 98.4% (95% CI: 97.5% −99.2%) of study participants were immune against rubella. Five women (0.6%) were in borderline category and 1% (8 women) was susceptible to rubella. The proportion of immune people in low and high incidence regions was 99.3% (95% CI: 97.8–99.9%), and 97.5% (95% CI: 96.4–98.5%), respectively (P = 0.05). Our data indicated that level of immunity to rubella in women of reproductive age in Iran is satisfactory. This finding indicates the achievement of Iran to the goal of high level of serum immunity against rubella among young women. © 2018, © 2018 Taylor & Francis Group, LLC.
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1. Seroepidemiology of Rubella in Women Under 25 Years Old Attending Medical Centers in Ahvaz, Iran in 2013, Jundishapur Journal of Microbiology (2015)