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Distribution of Intraocular Pressure, Central Corneal Thickness and Vertical Cup-To-Disc Ratio in a Healthy Iranian Population: The Yazd Eye Study Publisher Pubmed



Pakravan M1 ; Javadi MA1 ; Yazdani S1 ; Ghahari E1 ; Behroozi Z1 ; Soleimanizad R2 ; Moghimi S3 ; Nilforoushan N3 ; Zarei R3 ; Eslami Y3 ; Ghassami M1 ; Ziaei H1 ; Katibeh M1 ; Tabesh H1 Show All Authors
Authors
  1. Pakravan M1
  2. Javadi MA1
  3. Yazdani S1
  4. Ghahari E1
  5. Behroozi Z1
  6. Soleimanizad R2
  7. Moghimi S3
  8. Nilforoushan N3
  9. Zarei R3
  10. Eslami Y3
  11. Ghassami M1
  12. Ziaei H1
  13. Katibeh M1
  14. Tabesh H1
  15. Yaseri M4
Show Affiliations
Authors Affiliations
  1. 1. Ophthalmic Epidemiology and Prevention of Blindness Center, Shahid Beheshti University of Medical Science, Tehran, Iran
  2. 2. Shahid Sadooghi University of Medical Sciences, Yazd, Iran
  3. 3. Department of Ophthalmology and Eye Research Center, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Source: Acta Ophthalmologica Published:2017


Abstract

Purpose: To determine the distribution of intraocular pressure (IOP), central corneal thickness (CCT) and vertical cup-to-disc ratio (VCDR) in the healthy Iranian population. Methods: This population-based, epidemiologic study evaluated Iranian aged 40–80 years, residing in Yazd, Iran, in 2010–2011. Eligible subjects were selected by cluster random sampling. Each participant underwent an interview and ophthalmologic examination including slit lamp examination, Goldmann applanation tonometry, binocular optic disc evaluation, stereoscopic fundus photography, ultrasonic pachymetry and visual field testing. Results: Of 2320 eligible individuals, 2098 subjects (response rate of 90.4%) participated in the study. One eye from 1159 subjects (total of 2262 normal eyes) were randomly selected for the purpose of the study. Mean age was 53.1 ± 9.6 years. Mean IOP, CCT and VCDR were 14.2 ± 2.5 mmHg, 543 ± 37 μm and 0.32 ± 0.14, respectively. Multiple regression analysis showed a significant correlation between IOP and age (regression coefficient = 0.02 per year, p = 0.015), CCT (regression coefficient = 0.02 per micron, p < 0.001), Spherical equivalent (regression coefficient = −0.15 per dioptre, p = 0.0.024) and smoking (regression coefficient = 0.89 higher for smokers, p = 0.009); it also showed a significant correlation between CCT with spherical equivalent (regression coefficient = 3.6 per dioptre, p = 0.002) and IOP (regression coefficient = 3.6 per mmHG, p < 0.001). There was no significant correlation with VCDR. Conclusions: Mean IOP, CCT and VCDR were 14.2 ± 2.5 mmHg, 543 ± 35 μm and 0.32 ± 0.14, respectively, in healthy Iranians that is different from other ethnicities. It seems advisable to pay attention to ethnicity for interpretation of each person's variables. © 2016 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd