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The Role of Lipids in the Pathophysiology of Coronavirus Infections Publisher



Zandi M1, 2 ; Hosseini P1, 2 ; Soltani S1, 2 ; Rasooli A3 ; Moghadami M4 ; Nasimzadeh S5 ; Behnezhad F1
Authors
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Authors Affiliations
  1. 1. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Research Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Biochemistry, Faculty of Sciences, Payame Noor University, Tehran, Iran
  4. 4. Department of Medical Biotechnology, School of Medicine, Babol University of Medical Sciences, Babol, Iran
  5. 5. Department of Virology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Source: Osong Public Health and Research Perspectives Published:2021


Abstract

Coronaviruses, which have been known to cause diseases in animals since the 1930s, utilize cellular components during their replication cycle. Lipids play important roles in viral infection, as coronaviruses target cellular lipids and lipid metabolism to modify their host cells to become an optimal environment for viral replication. Therefore, lipids can be considered as potential targets for the development of antiviral agents. This review provides an overview of the roles of cellular lipids in different stages of the life cycle of coronaviruses. © 2021 Korea Disease Control and Prevention Agency.
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