Triflic Anhydride (Tf2o): An Efficient Catalyst for Electrophilic Activation of Amides

Triflic Anhydride (Tf2o): An Efficient Catalyst for Electrophilic Activation of Amides Publisher

Tashrifi Z¹ ; Mohammadikhanaposhtani M² ; Larijani B¹ ; Mahdavi M¹

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1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
2. Faculty of Fouman, College of Engineering, University of Tehran, Fouman, Iran

Source: ChemistrySelect Published:2021

Abstract

Tf2O (trifluoromethanesulfonic anhydride) as an electrophilic reagent has been increasingly attracting the attention of researchers over the last decade due to its capability in synthesizing a variety of N-heterocycles through activation of amides. This activation is associated with the formation of intermediates such as enolonium, imino/iminium, nitrilium and keteniminium triflate ions and isocyanate species which can lead to the synthesis of different types of N-heterocycles depending on the nature of the intermediates. In this review, we have summarized and classified the latest research in this area (from 2012 on) based on the type of intermediates produced from the triflic anhydride-catalyzed activation of amides. The findings are classified into five main categories, namely enolonium, imino/iminium, nitrilium and keteniminium intermediates ions and isocyanate species. © 2021 Wiley-VCH GmbH

Style	Citing Format
MLA	Tashrifi Z, et al.. "Triflic Anhydride (Tf2o): An Efficient Catalyst for Electrophilic Activation of Amides." ChemistrySelect, vol. 6, no. 21, 2021, pp. 5320-5328.
APA	Tashrifi Z, Mohammadikhanaposhtani M, Larijani B, Mahdavi M (2021). Triflic Anhydride (Tf2o): An Efficient Catalyst for Electrophilic Activation of Amides. ChemistrySelect, 6(21), 5320-5328.
Chicago	Tashrifi Z, Mohammadikhanaposhtani M, Larijani B, Mahdavi M. "Triflic Anhydride (Tf2o): An Efficient Catalyst for Electrophilic Activation of Amides." ChemistrySelect 6, no. 21 (2021): 5320-5328.
Harvard	Tashrifi Z et al. (2021) 'Triflic Anhydride (Tf2o): An Efficient Catalyst for Electrophilic Activation of Amides', ChemistrySelect, 6(21), pp. 5320-5328.
Vancouver	Tashrifi Z, Mohammadikhanaposhtani M, Larijani B, Mahdavi M. Triflic Anhydride (Tf2o): An Efficient Catalyst for Electrophilic Activation of Amides. ChemistrySelect. 2021;6(21):5320-5328.
BibTex	@article{ author = {Tashrifi Z and Mohammadikhanaposhtani M and Larijani B and Mahdavi M}, title = {Triflic Anhydride (Tf2o): An Efficient Catalyst for Electrophilic Activation of Amides}, journal = {ChemistrySelect}, volume = {6}, number = {21}, pages = {5320-5328}, year = {2021} }
RIS	TY - JOUR AU - Tashrifi Z AU - Mohammadikhanaposhtani M AU - Larijani B AU - Mahdavi M TI - Triflic Anhydride (Tf2o): An Efficient Catalyst for Electrophilic Activation of Amides JO - ChemistrySelect VL - 6 IS - 21 SP - 5320 EP - 5328 PY - 2021 ER -

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