The Impact of Bariatric Surgery Procedures on the Modulation of Cardiometabolic Risk Factors in Patients With Severe Obesity: A 12-Month Follow-Up Publisher Pubmed



Tabesh MR^{1, 2} ; Abolhasani M³ ; Zali MR⁴ ; Bagheri R⁵ ; Alipour M⁶ ; Cheraghloo N⁷ ; Asadzadehaghdaei H¹ ; Wong A⁸ ; Zahedi H⁹ ; Hobaby S¹⁰ ; Shadnoush M^{1, 11} ; Cheraghpour M¹ Show Affiliations
Source: Journal of International Medical Research Published:2022

Abstract

Objective: To evaluate the effects of one anastomosis gastric bypass (OAGB), Roux-en-Y gastric bypass (RYGB), and sleeve gastrectomy (SG) on cardiometabolic risk factors (CMRFs) in patients with severe obesity. Methods: This retrospective cohort study included patients with severe obesity who had undergone OAGB, RYGB, or SG between 2015 and 2017 and follow-up assessments over 12-months. Results: Among 485 included patients, anthropometric measurements, body composition, fasting blood glucose (FBG), lipid profile, and comorbidities were significantly improved for all three procedures throughout the follow-up period. Weight, % total weight loss (%TWL), body mass index, fat mass and fat mass to fat-free mass ratio improvements were higher with RYGB and OAGB than SG. There were no significant differences between procedures in all other variables. A significant trend toward remission rate of dyslipidemia and type 2 diabetes mellitus was observed with all three procedures, with no significant difference between the three groups. %TWL statistically correlated with fat mass, FBG, and triglycerides. Conclusions: OAGB, RYGB, and SG had a beneficial impact on CMRFs and comorbidities during 12 months of follow-up. Of note, RYGB and OAGB may result in better outcomes, particularly anthropometric and body composition indices. Further large-sample, long-term follow-up studies are required to expand on the present findings. © The Author(s) 2022.