Gender Differences in Post-Traumatic Stress Disorder and Depression Among Iranian Population With Substance Use Disorder Publisher



Merghati Khoei E¹ ; Rezaei Z² ; Mohraz M³ ; Brady KT⁴ ; Killeen T⁴ ; Korte JE⁵ ; Bayat A¹ ; Yousefi H¹ Show Affiliations
Source: Journal of Substance Use Published:2023

Abstract

Background: In a review of Iranian studies, no studies have yet to explore a relationship between substance use disorders (SUDs), depression and/or PTSD. In this paper, we report whether the Iranian women and men with SUDs exhibit differences in PTSD and depression. Methods: A cross-sectional study was performed on 600 SUDs patients in treatment. Assessments included socio demographic questionnaire, the Beck Depression Inventory II, and the PTSD Checklist. Data were analyzed using descriptive, chi-square (χ2) and logistic regression analysis. Results: PTSD was 61.5% in the study population. The mean PTSD score was 47.92 ± 12.07 for all men and women. The participants revealed mild, moderate, and severe depressive symptoms 19.7%, 24.3%, and 32.3%, respectively. Women were more likely than men to be diagnosed with PTSD (adjusted odds ratio (AOR) =1.82, 95%CI: 1.19, 2.80) and depression (AOR =1.65, 95%CI: 1.01, 2.77). In addition, marital status and job status were significantly associated with depression and PTSD. Conclusions: This study shows remarkably higher prevalence of PTSD and depression in drug using women than their male counterparts. The results illustrate a number of gender differences that may shed light on etiologic models of co-morbid SUDs, PTSD, and depression. © 2022 Taylor & Francis Group, LLC.