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Advice on Assistance and Protection From the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 2. on Preventing and Treating Health Effects From Acute, Prolonged, and Repeated Nerve Agent Exposure, and the Identification of Medical Countermeasures Able to Reduce or Eliminate the Longer Term Health Effects of Nerve Agents Publisher Pubmed



Timperley CM1 ; Abdollahi M2 ; Alamri AS3 ; Baulig A4 ; Benachour D5 ; Borrett V6, 7 ; Carino FA8 ; Geist M9 ; Gonzalez D10 ; Kane W11 ; Kovarik Z12 ; Martinezalvarez R13 ; Fusaro Mourao NM14 ; Neffe S15 Show All Authors
Authors
  1. Timperley CM1
  2. Abdollahi M2
  3. Alamri AS3
  4. Baulig A4
  5. Benachour D5
  6. Borrett V6, 7
  7. Carino FA8
  8. Geist M9
  9. Gonzalez D10
  10. Kane W11
  11. Kovarik Z12
  12. Martinezalvarez R13
  13. Fusaro Mourao NM14
  14. Neffe S15
  15. Raza SK16
  16. Rubaylo V17
  17. Suarez AG18
  18. Takeuchi K19
  19. Tang C20
  20. Trifiro F21
  21. Van Straten FM22
  22. Vanninen PS23
  23. Vucinic S24
  24. Zaitsev V25, 26
  25. Zafaruzzaman M27
  26. Zina MS28
  27. Holen S29
  28. Forman JE30, 34
  29. Alwan WS31, 32
  30. Suri V33

Source: Toxicology Published:2019


Abstract

The Scientific Advisory Board (SAB) of the Organisation for the Prohibition of Chemical Weapons (OPCW) has provided advice in relation to the Chemical Weapons Convention on assistance and protection. We present the SAB's response to a request from the OPCW Director-General in 2014 for information on the best practices for preventing and treating the health effects from acute, prolonged, and repeated organophosphorus nerve agent (NA) exposure. The report summarises pre- and post-exposure treatments, and developments in decontaminants and adsorbing materials, that at the time of the advice, were available for NAs. The updated information provided could assist medics and emergency responders unfamiliar with treatment and decontamination options related to exposure to NAs. The SAB recommended that developments in research on medical countermeasures and decontaminants for NAs should be monitored by the OPCW, and used in assistance and protection training courses and workshops organised through its capacity building programmes. © 2018 Elsevier B.V.