Tehran University of Medical Sciences

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Albumin-Based Biomaterial for Lung Tissue Engineering Applications Publisher



Aiyelabegan HT1, 2 ; Zaidi SSZ1, 2 ; Fanuel S1, 2 ; Eatemadi A1 ; Ebadi MTK1 ; Sadroddiny E1
Authors

Source: International Journal of Polymeric Materials and Polymeric Biomaterials Published:2016


Abstract

The role of albumin-based biomaterials in tissue engineering (TE) cannot be overemphasized. The authors review the role of albumin in lungs scaffold grafting, which promotes cell seeding. Albumin grafted on decellularized lungs scaffold is presented as a great support material for cell-tissue interaction as well as for ease in attachment, growth, and differentiation when seeded with different types of cells. Albumin scaffold fabrication from different sources is a promising approach that may facilitate medical treatments from bench-to-bed, although the role of this scaffold in lungs surfactant proteins regeneration and binding needs to be fully elucidated. © 2016 Taylor & Francis.