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Multiple Spontaneous Perforation of Small Bowel by Mycobacterium Avium Complex Infection in an Aids Patient Publisher



Hosamirudsari H1 ; Shahnavaz H2 ; Mahooti N3
Authors
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Authors Affiliations
  1. 1. Department of Infectious Diseases, Baharloo Hospital, Tehran University of Medical Sciences, Behdari St., Railway Sq., Tehran, Iran
  2. 2. Department of Pathology, Baharloo Hospital, Tehran University of Medical Sciences, Behdari St., Railway Sq., Tehran, Iran
  3. 3. Department of Surgery, Baharloo Hospital, Tehran University of Medical Sciences, Behdari St., Railway Sq., Tehran, Iran

Source: HIV and AIDS Review Published:2016


Abstract

Disseminated Mycobacterium avium complex (MAC) infections occur in late stage of AIDS. Highly active antiretroviral therapy (HAART) decreases the incidence of MAC infection, but patients with low CD4 counts who have no access to HAART, are remained at risk. The intestine is involved in disseminated MAC which causes gastrointestinal tract symptoms. Spontaneous perforation of small bowel, only ileum by disseminated MAC is documented in one case report. We present a rare case of disseminated MAC infection that led to the multiple spontaneous perforation of small intestine in ileum and cecum. The patient deceased, despite immediate surgical intervention. Mycobacterium avium complex is an important cause of multiple, spontaneous small bowel perforation. We recommend administrating MAC prophylaxis in HIV positive patients who do not have access to HAART therapy. © 2015 Polish AIDS Research Society.