Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Trends of 28 Days Case Fatality Rate After First Acute Myocardial Infarction in Isfahan, Iran, From 2000 to 2009



Mohammadian M1 ; Hosseini S2 ; Sadeghi M1 ; Sarrafzadegan N2 ; Salehiniya H3, 6 ; Roohafza H1 ; Khazaei S4 ; Mohammadianhafshejani A5, 6
Authors
Show Affiliations
Authors Affiliations
  1. 1. Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran
  5. 5. Department of Social Medicine, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
  6. 6. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Source: ARYA Atherosclerosis Published:2015

Abstract

Background: The purpose of the present study was the analysis of the trends in case fatality rate of acute myocardial infarction (AMI) in Isfahan, Iran. This analysis was performed based on gender, age groups, and type of AMI according to the International Classification of Diseases, version 10, during 2000-2009. Methods: Disregarding the Multinational Monitoring of Trends and Determinants in Cardiovascular Disease (MONICA), this cohort study considered all AMI events registered between 2000 and 2009 in 13 hospitals in Isfahan. All patients were followed for 28 days. In order to assess the case fatality rate, the Kaplan-Meier analysis, and to compare survival rate, log-rank test were used. Using the Cox regression model, 28 days case fatality hazard ratio (HR) was calculated. Results: In total, 12,900 patients with first AMI were entered into the study. Among them, 9307 (72.10%) were men and 3593 (27.90%) women. The mean age in all patients increased from 61.36 ± 12.19 in 2000-2001 to 62.15 ± 12.74 in 2008-2009, (P = 0.0070); in women, from 65.38 ± 10.95 to 67.15 ± 11.72 (P = 0.0200), and in men, from 59.75 ± 12.29 to 59.84 ± 12.54 (P = 0.0170),. In addition, the 28 days case fatality rate in 2000-2009 had a steady descending trend. Thus, it decreased from 11.20% in 2000-2001 to 07.90% in 2008-2009; in men, from 09.20% to 06.70%, and in women, from 16.10% to 10.90%. During the study, HR of case fatality rate in 2000-2001 declined; therefore, in 2002-2003, it was 0.93 [95% confidence interval (CI) = 0.77-1.11], in 2004-2005, 0.88 (95% CI = 0.73-1.04), in 2006-2007, 0.67 (95% CI = 0.56- 0.82), and in 2008-2009, 0.69 (95% CI = 0.56-0.82). Conclusion: In Isfahan, a reduction was observable in the trend of case fatality rate in both genders and all age groups. Thus, there was a 29.46% reduction in case fatality rate (27.17% in men, 32.29% in women) during the study period. © 2015, Isfahan University of Medical Sciences(IUMS). All rights reserved.
Related Docs
1. Prognostic Factors of 28 Days Survival Rate in Patients With a First Acute Myocardial Infarction Based on Gender in Isfahan, Iran (2000-2009), ARYA Atherosclerosis (2015)
2. Predictive Factors of Short-Term Survival From Acute Myocardial Infarction in Early and Late Patients in Isfahan and Najafabad, Iran, ARYA Atherosclerosis (2016)
3. A 10-Year Isfahan Cohort on Cardiovascular Disease As a Master Plan for a Multi-Generation Non-Communicable Disease Longitudinal Study: Methodology and Challenges, Journal of Human Hypertension (2019)
4. Determinants of Incident Metabolic Syndrome in a Middle Eastern Population: Isfahan Cohort Study, Metabolic Syndrome and Related Disorders (2017)
5. Persian Registry of Cardiovascular Disease (Prove): Design and Methodology, ARYA Atherosclerosis (2017)