Tehran University of Medical Sciences

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Rapid and Green Synthesis of 4H-Benzo[B]Pyrans Using Triethanolamine As an Efficient Homogeneous Catalyst Under Ambient Conditions Publisher



Rahnamafa R1 ; Moradi L1 ; Khoobi M2
Authors
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Authors Affiliations
  1. 1. Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, P.O. Box 8731753153, Kashan, Iran
  2. 2. Department of Pharmaceutical Biomaterials, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Source: Research on Chemical Intermediates Published:2020


Abstract

4H-benzo[b]pyrans were obtained rapidly in high yields using triethanolamine as an efficient, eco-friendly and low-cost basic catalyst. One-pot three-component condensation reaction of a series of aldehydes, malononitrile and 1,3-diketones was performed at room temperature. All the products were obtained in high-to-excellent yields and characterized in detail. Green, rapid and mild process, very short reaction times (1–12 min) and simple workup are some of the advantages of this method. © 2020, Springer Nature B.V.