Feeding-Based Treatment of Allergic Proctocolitis and Associated Clinical Outcomes Publisher Pubmed



Ahmadipour S^{1, 2, 3} ; Najafi M⁴ ; Motamed F⁴ ; Rahmani P⁴ Show Affiliations
Source: Clinical Nutrition ESPEN Published:2020

Abstract

Background: Allergic colitis (AC) is one of the most common etiologies of rectal bleeding in infants aged one to six months. Aim: The aim of this study is to apply step-by-step dietary restrictions in the mother's diet or change of infant formula fed thereby, to evaluate the subsequent clinical response. Methods: Sixty healthy infants whose clinical and evaluation results indicated proctocolitis in our outpatient gastroenterology clinic were included in this. They were divided into three groups according to the type of feeding; group 1 were exclusively breast fed, group 2 were exclusively formula fed and group 3 were fed with combination of both. In breast feeding women, discontinuation was allergenic food was studied in four stages; cow-related dairy products, soy, sesame and fast food (stage A), egg (stage B), corn, nuts and fish (stage C) and wheat (stage D). Results: Sixty newborns with age at symptom onset 3 days–20 days participated in the study. Up to the time of our initial evaluation, the mean age and weight of infants was 73.34 ± 1.00 day and 3292.71 ± 367.93 g, respectively. There was no significant difference in sex and the type of labor between the groups. Thirty-three infants had a history of eczema and the parents of 47 infants had a history of allergy, with the greatest prevalence in group one. Rectal bleeding in 50% of infants was halted after the elimination of allergenic feed in mother (15 in stage A, 8 in stage B and 7 in stage C). Ten infants needed extensive hydrolyzed formula and 20 needed amino acid-based formulas. Conclusions: There is no need for immediate use of amino acid or extensive hydrolyzed formulas in the first stage of blood in stool, perhaps discontinuing allergenic food in mothers could be the primary measure. © 2020 European Society for Clinical Nutrition and Metabolism