Evaluation of Quality of Life in Patients With Oral Cancer After Mandibular Resection: Comparing No Reconstruction, Reconstruction With Plate, and Reconstruction With Flap Publisher Pubmed



Davudov MM^{1, 2} ; Harirchi I¹ ; Arabkheradmand A¹ ; Garajei A¹ ; Mahmudzadeh H¹ ; Shirkhoda M¹ ; Motieelangroudi M¹ ; Mirzajani Z^{1, 2} ; Zebardast J¹ ; Montazeri A³ Show Affiliations
Source: Medicine (United States) Published:2019

Abstract

This cross-sectional study aimed to assess and compare quality of life in patients with advanced oral cavity tumors after mandibular resection in 3 groups (no reconstruction, reconstruction with plate, and reconstruction with flap) at the Cancer Institute, affiliated to Tehran University of Medical Sciences. Quality of life was measured using the European Organization for Research and Treatment of Cancer core quality of life questionnaire and European Organization for Research and Treatment of Cancer head and neck cancer-specific quality of life questionnaire-35 items. The comparison was tested using Kurskal-Wallis analysis. All 120 patients were entered into the study. The mean age of patients was 48.5 (standard deviation=18.1) years. Patients presented with advanced stage of the disease and underwent mandibular resection with no reconstruction (n=40), reconstruction with plate (n=41), and reconstruction with flap (n=39). The findings showed that in general, there were no statistically significant differences in quality of life among 3 groups except for speech problem (P=.4), dry mouth (P=.03), and feeling ill (P=.04). Although there were no significant differences in quality of life among patients in 3 groups, overall patients who received reconstruction with flap reported better functioning and fewer symptoms. Those who did not receive any reconstruction reported the worse conditions. © 2019 the Author(s). Published by Wolters Kluwer Health, Inc.