Tehran University of Medical Sciences

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Brain Metastasis From Esophageal Cancer Publisher



Keramati MR1 ; Esmaeilzadeh M2 ; Bashashati M3
Authors
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Authors Affiliations
  1. 1. Department of Surgery, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Neurosurgery, Hannover Medical School, Hannover, Germany
  3. 3. Center for Neurogastroenterology and GI Motility, Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX, United States

Source: Brain Metastases from Primary Tumors: Epidemiology# Biology# and Therapy of Melanoma and Other Cancers Published:2016


Abstract

Esophageal cancer is one of the common gastrointestinal cancers around the world. Lymph nodes, liver, and peritoneum are the most common sites of its metastasis. Rarely, it can also metastasize to the brain. The size of the primary tumor and the stage of disease seem to be associated with the brain metastasis, although the pathway that esophageal cancer cells take to reach the brain is not well recognized. Brain metastasis from esophageal cancer has a very poor prognosis and the literature on this topic is primarily built on case reports or small case series. Therefore, no clear management strategy has been defined for these patients. In this chapter, we discuss what is known and what needs to be recognized about the brain metastasis from esophageal cancer and cover possible diagnostic and therapeutic strategies in this situation. © 2016 Elsevier Inc. All rights reserved.