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The Effect of Algae Supplementation on Lipid Profile and Blood Pressure in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Publisher



Arzhang P1 ; Arghavan H2 ; Kazeminejad S3, 4 ; Mohammadi F2 ; Baniasadi MM3, 4 ; Bavani NG5 ; Darvishi H6 ; Azadbakht L3
Authors
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Authors Affiliations
  1. 1. Qods Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
  2. 2. Endocrinology and Nephrology Research Axis, CHU de Quebec - Universite Laval, Quebec, G1V 4G2, QC, Canada
  3. 3. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Students’ Scientific Research Centre, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
  6. 6. Department of Pharmacology and Toxicology, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Functional Foods Published:2024


Abstract

To assess the effects of algae supplementation on lipid profiles and blood pressure in adults, we conducted a systematic search in PubMed, Scopus, Web of Science, and Cochrane Library for relevant randomized controlled trials (RCTs). A total of 77 RCTs with 3686 participants were included. Algae supplementation significantly reduced triglycerides (TG) (WMD: −7.99 mg/dL, 95 % CI: −12.71, −3.26), total cholesterol (TC) (WMD: −11.01 mg/dL, 95 % CI: −14.26, −7.76), and low-density lipoprotein (LDL) (WMD: −10.17 mg/dL, 95 % CI: −13.12, −7.22) levels, while increasing high-density lipoprotein (HDL) (WMD: 1.66 mg/dL, 95 % CI: 0.73, 2.59). No significant changes were observed in the LDL/HDL ratio and systolic blood pressure (SBP), but diastolic blood pressure (DBP) significantly decreased (WMD: −1.71 mmHg, 95 % CI: −2.72, −0.71). These findings suggest that algae supplementation can improve cardiovascular health markers, although further research is needed to address the observed variability. © 2024 The Author(s)
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