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Nanoporous Structures-Based Biosensors for Environmental and Biomedical Diagnostics: Advancements, Opportunities, and Challenges Publisher



Nokandeh SM1 ; Eivazzadehkeihan R1 ; Salimi Bani M2 ; Zare I3 ; Kang H4, 5 ; Tavakkoli Yaraki M6 ; Mahdavi M7 ; Maleki A1 ; Varma RS8
Authors
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Authors Affiliations
  1. 1. Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, 16846-13114, Iran
  2. 2. Department of Optics and Photonics, Wroclaw University of Science and Technology, Wroclaw, Poland
  3. 3. Research and Development Department, Sina Medical Biochemistry Technologies Co., Ltd., Shiraz, 7178795844, Iran
  4. 4. Department of Materials Science and Engineering, Korea University, Seoul, 02841, South Korea
  5. 5. College of Medicine, Korea University, Seoul, 02841, South Korea
  6. 6. School of Natural Sciences, Faculty of Science and Engineering, Macquarie University, Sydney, 2109, NSW, Australia
  7. 7. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Centre of Excellence for Research in Sustainable Chemistry, Department of Chemistry, Federal University of Sao Carlos, SP, Sao Carlos, 13565-905, Brazil

Source: Coordination Chemistry Reviews Published:2025


Abstract

As emerging platforms, nanoporous-based biosensors have potentially useful applications for sensitive and selective detection of various analytes. The integration of nanoporous materials (e.g., nanocarbons, mesoporous, metal–organic frameworks (MOFs), and MOF-based nanocomposites, etc.) with various transduction techniques, such as electrochemical, optical, and mass-sensitized, has led to the development of biosensors for a wide spectrum of applications in healthcare, environmental monitoring, and food safety. These biosensors take advantage of the unique properties of nanoporous materials, such as tunable pore size and selective surface chemistry with high surface area, and enhance the interaction between the analyte and the recognition element. Overall, biosensors based on nanoporous material have very low limits of detection and appropriate linear range. This review focuses on recent developments in the design of biosensors based on nanoporous materials, including sensing mechanisms and applications. © 2024 Elsevier B.V.
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