Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! By
Effects of Zingiber Officinale in Complementary Care for Postoperative Complications: A Systematic Review Publisher



H Lalehgani HEDAYATALLAH ; A Amini ALI ; H Shakerin HADI
Authors

Source: Journal of HerbMed Pharmacology Published:2025


Abstract

Introduction: Postoperative complications are among the most common complications related to surgery or anesthetics, leading to longer treatment duration and extended hospitalization. So, we decided to explore the clinical outcomes of Zingiber officinale or ginger on postoperative complications. Methods: This study adhered to the PRISMA 2020 guidelines. To find relevant studies published before April 2, 2025, a comprehensive search was done in Scopus, Cochrane Library, Web of Science, and PubMed/MEDLINE. Predefined criteria for including and excluding studies were applied and duplicate entries were eliminated. The data extraction process concentrated on study characteristics, interventions, and key outcomes. Results: The included studies demonstrated that Z. officinale was generally effective in alleviating the severity and frequency of postoperative nausea and vomiting (PONV) compared to standard antiemetics, with several studies reporting a significant decrease in nausea intensity, reduced need for antiemetic medications and improved patient satisfaction. However, the incidence of vomiting was not consistently affected. Moreover, aromatherapy with ginger showed variable effectiveness, with some studies indicating borderline or non-significant effects. Regarding postoperative pain, ginger demonstrated comparable analgesic effects to nonsteroidal anti-inflammatory drugs in several trials, with significant pain reduction observed. Additional benefits included reduced postoperative shivering, anxiety scores, and decreased severity of post-cesarean abdominal distention. However, effects on bowel function and ileus were inconsistent. Conclusion: Z. officinale shows promise as a safe complementary treatment for reducing postoperative complications in various surgical settings. However, additional clinical research is necessary to draw a more definitive conclusion. © 2025 Elsevier B.V., All rights reserved.
Related Docs
View other Related Docs
1. Evaluation and Comparison of Two Different Combined Regimens for Prophylaxis of Nausea and Vomiting After Laparoscopic Bariatric Surgery: A Double-Blinded Randomized Clinical Trial, Acta Medica Iranica (2023)
2. Prophylactic Administration of Diphenhydramine/Acetaminophen and Ondansetron Reduced Postoperative Nausea and Vomiting and Pain Following Laparoscopic Sleeve Gastrectomy: A Randomized Controlled Trial, Obesity Surgery (2021)
3. Comparison of Post‐Operative Nausea and Vomiting With Intravenous Versus Inhalational Anesthesia in Laparotomic Abdominal Surgery: A Randomized Clinical Trial; [Comparacao Entre Anestesia Intravenosa E Inalatoria Na Nausea E Vomito Pos‐Operatorios Em Laparotomia: Estudo Clinico Randomizado], Brazilian Journal of Anesthesiology (2020)
Experts (# of related papers)
View all Related Experts
Pejman Pourfakhr (3)
Mojgan Rahimi (3)
Other Related Docs
4. The Effect of Preoperative Oral Melatonin on Postoperative Pain After Lumbar Disc Surgery: A Double-Blinded Randomized Clinical Trial, Ethiopian journal of health sciences (2022)
5. The Effect of Ondansetron and Atropine Administration on Postoperative Nausea and Vomiting and Duration of Recovery Stay in Patients Who Undergoing Strabismus Surgery, Tehran University Medical Journal (2020)
6. Comparison of the Efficacy of Two Pre-Treatment Medication of Dexmedetomedine-Fentanyl and Midazolam-Fentanyl in Cataract Surgery, Tehran University Medical Journal (2020)
7. The Effect of Intravenous Dextrose Administration for Prevention of Post-Operative Nausea and Vomiting After Laparoscopic Cholecystectomy: A Double-Blind, Randomised Controlled Trial, Indian Journal of Anaesthesia (2017)
8. Prevalence of Postoperative Nausea and Vomiting in Orthopedic Patients in Imam Khomeini Hospital Complex During 2018-2019: A Cross-Sectional Study, Archives of Anesthesiology and Critical Care (2023)
9. Effect of Pregabalin on Morphine Consumption, Sleep, Mood and Ability to Change Position After Colorectal Cancer Surgery, Trauma Monthly (2021)
10. Incidence of Postoperative Vomiting and Laryngospasm in Pediatric Anesthesia Using Two Methods: Controlled Ventilation and Spontaneous Respiration, Shiraz E Medical Journal (2015)
11. Effect of Intravenous Acetaminophen on Postoperative Pain in Vitrectomy: A Randomized, Double-Blind, Clinical Trial, Anesthesiology and Pain Medicine (2017)
12. The Effect of Gabapentin on Reducing Pain After Laparoscopic Gastric Bypass Surgery in Patients With Morbid Obesity: A Randomized Clinical Trial, Anesthesiology and Pain Medicine (2015)
13. Effect of Preoperative Duloxetine on Opioid Consumption in Women Undergoing Abdominal Hysterectomy: A Randomized, Double-Blinded, Placebo-Controlled Trial, Anesthesiology and Pain Medicine (2020)
14. Three-Agent Preemptive Analgesia, Pregabalin-Acetaminophen-Naproxen, in Laparotomy for Cancer: A Randomized Clinical Trial, Anesthesiology and Pain Medicine (2017)
15. Intraoperative Administration of Methadone Reduced Postoperative Pain and Opioid Consumption Following Ca-Daveric Renal Transplantation: A Randomized Controlled Trial, Frontiers in Emergency Medicine (2023)
16. Post-Operative Pain Management With Meloxicam: A Systematic Literature Review in the Field of Dentistry, Oral Surgery (2020)
17. Comparing the Effect of Acupressure and Oral Midazolam on Controlling Preoperative Anxiety in Children: A Randomized Trial, Archives of Anesthesiology and Critical Care (2024)
18. Efficacy of Laparoscopic Transversus Abdominis Plane Block on Postoperative Pain Management and Surgery Side Effects in Laparoscopic Bariatric Surgeries, Langenbeck's Archives of Surgery (2022)
19. Pain Management Following Septorhinoplasty Surgery: Evidence From a Systematic Review, European Archives of Oto-Rhino-Laryngology (2023)
20. Accessing the Efficacy and Peri-Operative Adverse Effects of Three Different Hyperbaric Bupivacaine 0.5% Dosages for Spinal Anesthesia Induction in Lower Limb Orthopedic Surgeries: A Randomized Clinical Trial, BMC Anesthesiology (2024)