Association of Preoperative Hemoglobin A1c With In-Hospital Mortality Following Valvular Heart Surgery Publisher Pubmed



Shoghli M¹ ; Jain R² ; Boroumand M¹ ; Ziaee S¹ ; Rafiee A³ ; Pourgholi L¹ ; Shafiee A¹ ; Jalali A¹ ; Mortazavi SH¹ ; Ahmadi Tafti SH¹ Show Affiliations
Source: Brazilian Journal of Cardiovascular Surgery Published:2020

Abstract

Objective: To determine the association between the preoperative level of hemoglobin A1c (HbAlc) and in-hospital mortality in patients who underwent valvular heart surgery in our center in a retrospective cohort. Methods: In this retrospective consecutive cohort study, patients with type 2 diabetes mellitus who were referred to our center for elective valvular surgery were enrolled and followed up. The endpoint of this study was in-hospital mortality. Based on the level of HbA1c, patients were dichotomized around a level of 7% into two groups: Exposed patients with HbA1c > 7% and unexposed patients with HbA1c < 7%. Then, the study variables were compared between the two groups. Results: Two hundred twenty-four diabetic patients who were candidates for valvular surgery were enrolled; 106 patients (47.3%) had HbA1c < 7%, and 118 patients (52.6%) had HbA1c > 7%. The duration of diabetes was higher in patients with HbA1c > 7% (P=0.007). Thirteen (5.8%) patients died during hospital admission, of which nine patients were in the high HbA1c group. There was no significant difference between the groups regarding in-hospital mortality (P=0.899). Both the unadjusted and adjusted logistic regression models showed that HbA1c was not a predictor for in-hospital mortality (P=0.227 and P=0.388, respectively) Conclusion: This study showed no association between preoperative HbA1c levels and in-hospital mortality in candidates for valvular heart surgery. © 2020, Sociedade Brasileira de Cirurgia Cardiovascular. All rights reserved.