Tehran University of Medical Sciences

Science Communicator Platform

Share By
Association of Preoperative Hemoglobin A1c With In-Hospital Mortality Following Valvular Heart Surgery Publisher Pubmed

Summary: Does preoperative blood sugar impact heart surgery outcomes? This study found no link between HbA1c levels and in-hospital mortality for diabetic patients. #HeartSurgery #Diabetes

Shoghli M1 ; Jain R2 ; Boroumand M1 ; Ziaee S1 ; Rafiee A3 ; Pourgholi L1 ; Shafiee A1 ; Jalali A1 ; Mortazavi SH1 ; Ahmadi Tafti SH1
Authors

Source: Brazilian Journal of Cardiovascular Surgery Published:2020


Abstract

Objective: To determine the association between the preoperative level of hemoglobin A1c (HbAlc) and in-hospital mortality in patients who underwent valvular heart surgery in our center in a retrospective cohort. Methods: In this retrospective consecutive cohort study, patients with type 2 diabetes mellitus who were referred to our center for elective valvular surgery were enrolled and followed up. The endpoint of this study was in-hospital mortality. Based on the level of HbA1c, patients were dichotomized around a level of 7% into two groups: Exposed patients with HbA1c > 7% and unexposed patients with HbA1c < 7%. Then, the study variables were compared between the two groups. Results: Two hundred twenty-four diabetic patients who were candidates for valvular surgery were enrolled; 106 patients (47.3%) had HbA1c < 7%, and 118 patients (52.6%) had HbA1c > 7%. The duration of diabetes was higher in patients with HbA1c > 7% (P=0.007). Thirteen (5.8%) patients died during hospital admission, of which nine patients were in the high HbA1c group. There was no significant difference between the groups regarding in-hospital mortality (P=0.899). Both the unadjusted and adjusted logistic regression models showed that HbA1c was not a predictor for in-hospital mortality (P=0.227 and P=0.388, respectively) Conclusion: This study showed no association between preoperative HbA1c levels and in-hospital mortality in candidates for valvular heart surgery. © 2020, Sociedade Brasileira de Cirurgia Cardiovascular. All rights reserved.
Related Docs
View other Related Docs
1. Clinical and Laboratory Characteristics of Patients With Hypertension Admitted to Baharloo Hospital in Tehran With a Diagnosis of Covid-19 and Its Association With Mortality in 2020, Journal of Knowledge and Health in Basic Medical Sciences (2021)
2. Mortality Across the Spectrum of Hemoglobin Level in Patients Undergoing Surgical Coronary Revascularization, Clinical Cardiology (2023)
3. Iranian Patients With Diabetes and Covid-19-Associated Mucormycosis: Characteristics, Manifestations, and Mortality Risk Factors, International Journal of Diabetes in Developing Countries (2024)
Experts (# of related papers)
View all Related Experts
Mohammadreza Salehi (3)
Samaneh Akbarpour (2)
Association of Preoperative Hemoglobin A1c With In-Hospital Mortality Following Valvular Heart Surgery
Other Related Docs
4. In-Hospital Mortality in Patients With Lower Gastrointestinal Bleeding: Development and Validation of a Prediction Score, Endoscopy (2025)
5. Comparison of Once-Daily Versus Twice-Daily Injection of Insulin Detemir in Children With Type 1 Diabetes Mellitus, Iranian Journal of Pediatrics (2022)
6. Predictive Factors of Short-Term Survival From Acute Myocardial Infarction in Early and Late Patients in Isfahan and Najafabad, Iran, ARYA Atherosclerosis (2016)
7. The Effect of Preoperative Creatinine Clearances on Postoperative Oxygenation in Coronary Artery Bypass Grafting: A Cohort Study, Acta Medica Iranica (2018)
8. Different Combinations of Glucose Tolerance and Blood Pressure Status and Incident Cardiovascular Disease and All-Cause Mortality Events, Journal of Human Hypertension (2017)
9. Neutrophil-To-Lymphocyte Ratio Cut-Off Point for Covid-19 Mortality: A Retrospective Study, Acta Medica Iranica (2022)
10. Risk Factors of In-Hospital Mortality for Isolated On-Pump Coronary Artery Bypass Graft Surgery in the Northeast of Iran From 2007 to 2016, Irish Journal of Medical Science (2023)
11. Clinical Manifestation of Patients Who Died Due to Covid-19; a Retrospective Study From Qom-Iran, Archives of Iranian Medicine (2020)
12. Validity of Hemoglobin A1c Before 20 Weeks of Gestation for Prediction of Gestational Diabetes Mellitus, Iranian Journal of Obstetrics# Gynecology and Infertility (2020)
13. Effects of Renin-Angiotensin-Aldosterone Inhibitors on Early Outcomes of Hypertensive Covid-19 Patients: A Randomized Triple-Blind Clinical Trial, American Journal of Hypertension (2021)
14. The Prognostic Ability of On-Admission Hemoglobin Levels in Children With Covid-19: The Picu Experience at a Tertiary Hospital in Iran, Archives of Pediatric Infectious Diseases (2025)
15. Comparison of Pulmonary Emboli Management Between Pulmonary Emboli Response Team and the Conventional Method: The First Study From Iran, Critical Pathways in Cardiology (2022)
16. Prevalence and Risk Factors of Hypoxemia After Coronary Artery Bypass Grafting: The Time to Change Our Conceptions, Journal of Tehran University Heart Center (2019)
17. Survival Analysis and Its Associated Factors of Beta Thalassemia Major in Hamadan Province, Iranian Journal of Medical Sciences (2015)
18. Comparison of Endovascular Aneurysm Repair (Evar) With Open Surgical Repair in Elective Patients With Abdominal Aortic Aneurysm Performed by Vascular Surgeons: One-Year Outcome, International Journal of Pharmaceutical Research (2020)
19. Effects of Two Different Levels of Positive End-Expiratory Pressure on the Duration of Intubation in Patients Undergoing Coronary Artery Bypass Graft Surgery, Iranian Heart Journal (2020)
20. Risk Factors of Death in Mechanically Ventilated Covid-19 Patients: A Multi-Center Study From Iran, Acta Medica Iranica (2023)