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Health State Utilities for Patient’S Current Health From Bipolar Type I Disorder Pubmed



Banihashemian M1 ; Rashidian A2 ; Gholamian F1 ; Parsaeian M3 ; Moradi N4 ; Amini H5, 6
Authors
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Authors Affiliations
  1. 1. Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Epidemiology and Biostatistics, School of Public Health and Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. School of Pharmacy, Shahid Beheshti University of Medical sciences, Tehran, Iran
  5. 5. Department of Psychiatry, Roozbeh Hospital, Psychosomatic Medicine Research Center, Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Psychiatry, Roozbeh Hospital, South Kargar Avenue, Tehran, 13337 95914, Iran

Source: Journal of Mental Health Policy and Economics Published:2018


Abstract

Background: Bipolar Type I Disorder (BID) is a disabling mental disorder among young adults that places enormous psychological, social, and economic burdens on patients, their families, and health care systems and decreases quality of life (QOL). Few studies have investigated the quality-adjusted life-years (QALY), health state preferences, and utilities in patients with BID. Aim of Study: The aim of this study was to elicit health state utilities for current health among a sample of individuals with BID irrespective of their clinical conditions at the time of evaluation. Methods: One hundred individuals with BID were consecutively enrolled in this cross-sectional study. Preferences were elicited from patients with visual analogous scale (VAS) and time trade-off (TTO). To assess quality of life, the Farsi version of the World Health Organization’s QOL Instrument-Short Version (WHOQOL-BREF) was used. In addition, health state was assessed with the Short Form-36 (SF-36) health survey, and then a specially- derived reduced version of the SF-36 (the ‘SF-6D’) was calculated as an alternative to existing preference-based measures of health for conducting economic evaluation of various interventions. Moreover, several clinical measures were administered to participants. Results: The mean ( S.D.) VAS, TTO, and SF-6D utility scores were 0.59 ( 0.21), 0.44 ( 0.33), and 0.61 ( 0.11), respectively. There were significant associations of most selected clinical characteristics with VAS and TTO scores. Additionally, there were strong correlations between all domains of WHOQOL-BREF and VAS scores as well as moderate to strong correlations with TTO scores. Furthermore, there were strong correlations between all scales of SF-36 scores and VAS scores as well as moderate to strong correlations between the scales of SF-36 scores and TTO scores. © 2018 ICMPE
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