Experimental Animal Models of Chronic Inflammation

Experimental Animal Models of Chronic Inflammation Publisher

Rafiyan M¹ ; Sadeghmousavi S¹ ; Akbarzadeh M¹ ; Rezaei N^{2, 3, 4}

Show Affiliations

1. Animal Model Integrated Network (AMIN), Universal Scientific Education & Research Network (USERN), Tehran, Iran
2. Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
4. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Current Research in Immunology Published:2023

Abstract

Inflammation is a general term for a wide variety of both physiological and pathophysiological processes in the body which primarily prevents the body from diseases and helps to remove dead tissues. It has a crucial part in the body immune system. Tissue damage can recruit inflammatory cells and cytokines and induce inflammation. Inflammation can be classified as acute, sub-acute, and chronic. If it remained unresolved and lasted for prolonged periods, it would be considered as chronic inflammation (CI), which consequently exacerbates tissue damage in different organs. CI is the main pathophysiological cause of many disorders such as obesity, diabetes, arthritis, myocardial infarction, and cancer. Thus, it is critical to investigate different mechanisms involved in CI to understand its processes and to find proper anti-inflammatory therapeutic approaches for it. Animal models are one of the most useful tools for study about different diseases and mechanisms in the body, and are important in pharmacological studies to find proper treatments. In this study, we discussed the various experimental animal models that have been used to recreate CI which can help us to enhance the understanding of CI mechanisms in human and contribute to the development of potent new therapies. © 2023 The Authors

Style	Citing Format
MLA	Rafiyan M, et al.. "Experimental Animal Models of Chronic Inflammation." Current Research in Immunology, vol. 4, no. , 2023, pp. -.
APA	Rafiyan M, Sadeghmousavi S, Akbarzadeh M, Rezaei N (2023). Experimental Animal Models of Chronic Inflammation. Current Research in Immunology, 4(), -.
Chicago	Rafiyan M, Sadeghmousavi S, Akbarzadeh M, Rezaei N. "Experimental Animal Models of Chronic Inflammation." Current Research in Immunology 4, no. (2023): -.
Harvard	Rafiyan M et al. (2023) 'Experimental Animal Models of Chronic Inflammation', Current Research in Immunology, 4(), pp. -.
Vancouver	Rafiyan M, Sadeghmousavi S, Akbarzadeh M, Rezaei N. Experimental Animal Models of Chronic Inflammation. Current Research in Immunology. 2023;4():-.
BibTex	@article{ author = {Rafiyan M and Sadeghmousavi S and Akbarzadeh M and Rezaei N}, title = {Experimental Animal Models of Chronic Inflammation}, journal = {Current Research in Immunology}, volume = {4}, number = {}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Rafiyan M AU - Sadeghmousavi S AU - Akbarzadeh M AU - Rezaei N TI - Experimental Animal Models of Chronic Inflammation JO - Current Research in Immunology VL - 4 IS - SP - EP - PY - 2023 ER -

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Abstract