Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Using a Combination of Superb Microvascular Imaging and Other Auxiliary Ultrasound Techniques to Increase the Accuracy of Gray-Scale Ultrasound for Breast Masses Publisher Pubmed



Abedi M1 ; Sahebi L2 ; Eslami B3 ; Saberi A4 ; Orouji M5 ; Alipour S3, 4 ; Shahsavarhaghighi S3, 6
Authors
Show Affiliations
Authors Affiliations
  1. 1. Radiology Fellow, Ballarat Base Hospital, Ballarat, VIC, Australia
  2. 2. Maternal, Fetal and Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Breast Diseases Research Center, Cancer Institute, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex, Keshavarz Blvd., Tehran, Iran
  4. 4. Department of Surgery, Arash Women’s Hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Nursing, Arash Women’s Hospital, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: BMC Cancer Published:2024


Abstract

Background: Breast ultrasound is highly sensitive, but its specificity is not as high for detecting malignant lesions. Auxiliary modalities like elastography, Color and Power Doppler ultrasound are used as adjuncts to yield both a high sensitivity and specificity. Superb microvascular imaging (SMI) is a newer modality with more accuracy for detecting breast lesions. In this study, our goal was to investigate the role of SMI as an adjunct to ultrasound and find a suitable combination model for the evaluation of breast masses. Methods: In this cross-sectional study, 132 women with 172 breast masses who underwent ultrasound-guided biopsy were included. The ultrasound features of the lesion, the strain ratio in strain elastography, the number of vessels for each lesion, their morphology and distribution in Doppler and Power Doppler ultrasound and SMI were recorded for each lesion. A vascular score and a vascular ratio were defined. Results: In the histologic examination, 31 lesions (18%) were malignant and 141 lesions (82%) were benign. The vascular score was more accurate than the vascular ratio in all three modalities. The predictive ability of strain ratio was higher than Doppler and Power Doppler ultrasound and SMI. Adding SMI alone to ultrasound increased the specificity from 46.10% to 61.2% and the accuracy from 55.80% to 70.11%. In the combination of ultrasound with other modalities, the best was the combination of ultrasound, strain elastography, and SMI; which yielded a specificity and sensitivity of 100% and 74.4%, respectively. Conclusion: Adding SMI and STE modalities as adjuncts to ultrasound lowers the chance of missing malignant lesions and reduces unnecessary biopsies of breast lesions. A study with a larger sample size using this combination model to evaluate the accuracy with greater precision is recommended. © The Author(s) 2024.