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Complications of Transcatheter Paravalvular Leak Device Closure of Mitral Valve: An Updated Review of the Literature and a Rare Case Presentation Publisher Pubmed



Jenab Y1 ; Nourian S2 ; Hosseini Mohammadi NS1, 3 ; Mohsenibadalabadi R1 ; Hosseini K1, 3 ; Zakavi S1, 4 ; Ates I5
Authors
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Authors Affiliations
  1. 1. Tehran Heart Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Firoozgar Clinical Research and Development Center, Iran University of Medical Sciences, Tehran, Iran
  3. 3. Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Science, Tehran, Iran
  4. 4. Students' Scientific Research Center (SSRC), Tehran University of Medical Science, Tehran, Iran
  5. 5. Faculty of Healthscience, Bahcesehir University, Istanbul, Turkey

Source: Clinical Cardiology Published:2024


Abstract

Paravalvular leak (PVL) is an uncommon complication of prosthetic valve implantation, which can lead to infective endocarditis, heart failure, and hemolytic anemia. Surgical reintervention of PVLs is associated with high mortality rates. Transcatheter PVL closure (TPVLc) has emerged as an alternative to surgical reoperation. This method provides a high success rate with a low rate of complications. This article reviews the pathogenesis, clinical manifestation, diagnosis, and management of PVL and complications following TPVLc. Besides, we presented a case of a patient with severe PVL following mitral valve replacement, who experienced complete heart block (CHB) during TPVLc. The first TPVLc procedure failed in our patient due to possible AV-node insult during catheterization. After 1 week of persistent CHB, a permanent pacemaker was implanted. The defect was successfully passed using the previous attempt. Considering the advantages of TPVLc, procedure failure should be regarded as a concern. TPVLc should be performed by experienced medical teams in carefully selected patients. © 2024 The Authors. Clinical Cardiology published by Wiley Periodicals, LLC.