Interactions of Colorectal Cancer, Dietary Fats, and Polymorphisms of Arachidonate Lipoxygenase and Cyclooxygenase Genes: A Literature Review

Interactions of Colorectal Cancer, Dietary Fats, and Polymorphisms of Arachidonate Lipoxygenase and Cyclooxygenase Genes: A Literature Review Publisher

Gholamalizadeh M¹ ; Majidi N² ; Tajaddod S² ; Abdollahi S³ ; Poorhosseini SM⁴ ; Ahmadzadeh M⁵ ; Naimi Joubani M⁶ ; Mirzaei Dahka S⁷ ; Shafaei H⁷ ; Hajiesmaeil M⁸ ; Alizadeh A⁹ ; Doaei S¹⁰ ; Houshiarrad A¹¹

Show Affiliations

1. Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2. Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran
3. Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Medical Genetics, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
5. Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6. Research Center of Health and Enviroment, School of Health, Guilan University of Medical Sciences, Rasht, Iran
7. Nursing and Midwifery School, Guilan University of Medical Sciences, Rasht, Iran
8. Department of Biology and Biotechnology â€�Charles Darwinâ€�, Sapienza University of Rome, Rome, Italy
9. Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
10. Reproductive Health Research Center, Department of Obstetrics and Gynecology, School of Medicine, Al-Zahra Hospital, Guilan University of Medical Sciences, Rasht, Iran
11. Dept. of Nutrition Research, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Frontiers in Oncology Published:2022

Abstract

Objective: Genetics and dietary factors play important roles in the development of colorectal cancer (CRC). However, the underlying mechanisms of the interactions between CRC, gene polymorphisms, and dietary fat are unclear. This review study investigated the effects of polymorphisms of arachidonate lipoxygenase (ALOX) and cyclooxygenase (COX) genes in the association between CRC and dietary fat. Methods: All the related papers published from 2000 to 2022 were collected from different databases such as PubMed, Science Direct, Scopus, and Cochran using related keywords such as colorectal cancer, ALOX, COX, polymorphism, and dietary fat. Non-English and unrelated documents were excluded. Results: Some single-nucleotide polymorphisms (SNPs) in the ALOX and COX genes, such as rs2228065, rs6413416, and rs4986832 in the ALOX gene, and rs689465 in the COX gene may play significant roles in the association between the risk of CRC and dietary fats. SNPs of ALOX and COX genes may influence the effects of dietary fatty acids on the risk of CRC. Conclusion: Some polymorphisms of the ALOX and COX genes may have important roles in the effects of dietary fat on the risk of CRC. If future studies confirm these results, dietary recommendations for preventing colorectal cancer may be personalized based on the genotype of the ALOX and COX genes. Copyright © 2022 Gholamalizadeh, Majidi, Tajaddod, Abdollahi, Poorhosseini, Ahmadzadeh, Naimi Joubani, Mirzaei Dahka, Shafaei, Hajiesmaeil, Alizadeh, Doaei and Houshiar-Rad.

2. Prostaglandin Synthase 2/Cyclooxygenase 2 Gene Polymorphisms and Susceptibility to Urothelial Bladder Cancer in an Iranian Population, Middle East Journal of Cancer (2022)

3. Establishing Core Data Elements for Colorectal Cancer and Mapping to Fhir Resources: Towards Interoperable Iranian Health Information Systems, Journal of Education and Health Promotion (2025)

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Farshad Sharifi (1)

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Style	Citing Format
MLA	Gholamalizadeh M, et al.. "Interactions of Colorectal Cancer, Dietary Fats, and Polymorphisms of Arachidonate Lipoxygenase and Cyclooxygenase Genes: A Literature Review." Frontiers in Oncology, vol. 12, no. , 2022, pp. -.
APA	Gholamalizadeh M, Majidi N, Tajaddod S, Abdollahi S, Poorhosseini SM, Ahmadzadeh M, Naimi Joubani M, Mirzaei Dahka S, Shafaei H, Hajiesmaeil M, Alizadeh A, Doaei S, Houshiarrad A (2022). Interactions of Colorectal Cancer, Dietary Fats, and Polymorphisms of Arachidonate Lipoxygenase and Cyclooxygenase Genes: A Literature Review. Frontiers in Oncology, 12(), -.
Chicago	Gholamalizadeh M, Majidi N, Tajaddod S, Abdollahi S, Poorhosseini SM, Ahmadzadeh M, Naimi Joubani M, et al.. "Interactions of Colorectal Cancer, Dietary Fats, and Polymorphisms of Arachidonate Lipoxygenase and Cyclooxygenase Genes: A Literature Review." Frontiers in Oncology 12, no. (2022): -.
Harvard	Gholamalizadeh M et al. (2022) 'Interactions of Colorectal Cancer, Dietary Fats, and Polymorphisms of Arachidonate Lipoxygenase and Cyclooxygenase Genes: A Literature Review', Frontiers in Oncology, 12(), pp. -.
Vancouver	Gholamalizadeh M, Majidi N, Tajaddod S, Abdollahi S, Poorhosseini SM, Ahmadzadeh M, et al.. Interactions of Colorectal Cancer, Dietary Fats, and Polymorphisms of Arachidonate Lipoxygenase and Cyclooxygenase Genes: A Literature Review. Frontiers in Oncology. 2022;12():-.
BibTex	@article{ author = {Gholamalizadeh M and Majidi N and Tajaddod S and Abdollahi S and Poorhosseini SM and Ahmadzadeh M and Naimi Joubani M and Mirzaei Dahka S and Shafaei H and Hajiesmaeil M and Alizadeh A and Doaei S and Houshiarrad A}, title = {Interactions of Colorectal Cancer, Dietary Fats, and Polymorphisms of Arachidonate Lipoxygenase and Cyclooxygenase Genes: A Literature Review}, journal = {Frontiers in Oncology}, volume = {12}, number = {}, pages = {-}, year = {2022} }
RIS	TY - JOUR AU - Gholamalizadeh M AU - Majidi N AU - Tajaddod S AU - Abdollahi S AU - Poorhosseini SM AU - Ahmadzadeh M AU - Naimi Joubani M AU - Mirzaei Dahka S AU - Shafaei H AU - Hajiesmaeil M AU - Alizadeh A AU - Doaei S AU - Houshiarrad A TI - Interactions of Colorectal Cancer, Dietary Fats, and Polymorphisms of Arachidonate Lipoxygenase and Cyclooxygenase Genes: A Literature Review JO - Frontiers in Oncology VL - 12 IS - SP - EP - PY - 2022 ER -

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