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Factors Associated With Anxiety in Premature Coronary Artery Disease Patients: Thc-Pac Study Pubmed



Abbasi SH1 ; Kassaian SE1 ; Sadeghian S1 ; Karimi A1 ; Saadat S2 ; Peyvandi F3, 4 ; Jalali A1 ; Davarpasand T1 ; Akhondzadeh S5 ; Shahmansouri N1 ; Boroumand MA1 ; Lotfitokaldany M1 ; Abchouyeh MA1 ; Isfahani FA1 Show All Authors
Authors
  1. Abbasi SH1
  2. Kassaian SE1
  3. Sadeghian S1
  4. Karimi A1
  5. Saadat S2
  6. Peyvandi F3, 4
  7. Jalali A1
  8. Davarpasand T1
  9. Akhondzadeh S5
  10. Shahmansouri N1
  11. Boroumand MA1
  12. Lotfitokaldany M1
  13. Abchouyeh MA1
  14. Isfahani FA1
  15. Rosendaal F6
Show Affiliations
Authors Affiliations
  1. 1. Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Sina Trauma Research Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico Milano, Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, Milan, Italy
  4. 4. Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Milan, Italy
  5. 5. Psychiatric Research Center, Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Clinical Epidemiology and Department of Thrombosis and Haemostasis, Leiden University Medical Center, Leiden, Netherlands

Source: Acta Medica Iranica Published:2016


Abstract

Background: Anxiety may negatively affect the course of coronary artery disease (CAD). The aim of this study was to assess which factors are associated with anxiety in young adults with CAD. A cohort of individuals with premature coronary artery disease was formed between 2004-2011, as the Tehran Heart Center's Premature Coronary Atherosclerosis Cohort (THC-PAC) study. Patients (men ≤ 45-year-old, and women ≤ 55-year-old) were visited between March 2013 and February 2014. All participants were examined, and their demographic, clinical, and laboratory data were collected. Then, all participants filled in the Beck Anxiety Inventory. Logistic regression models were used to identifying factors related to anxiety in both sexes. During the study, 708 patients (mean [SD] age: 45.3 [5.8] y, men: 48.2%) were visited. Anxiety was present in 53.0% of participants (66.0% of women and 39.0% of men). The logistic regressions model showed that the associated factors for anxiety in men were opium usage (OR=1.89, 95%CI: 1.09-3.27), positive family history (OR=1.49, 95%CI: 0.94-2.35), and creatinine serum level (OR=1.17, 95%CI: 1.05-1.303); and in women were major adverse cardiac events (MACE) during follow-up (OR=2.30, 95%CI: 1.25-4.23), hypertension (OR=1.71, 95%CI: 1.07-2.73) and the duration of CAD (OR=0.99, 95%CI: 0.98-1.00). In premature CAD patients, the determinants of anxiety seem to be different in each sex. Opium usage, positive family history of CAD, and creatinine serum levels in men, and MACE, hypertension, and duration of CAD in women appear the relevant factors in this regard. © 2016 Tehran University of Medical Sciences. All rights reserved.
Related Docs
1. Factors Associated With Depressive Symptoms in Young Adults With Coronary Artery Disease: Tehran Heart Center's Premature Coronary Atherosclerosis Cohort (Thc-Pac) Study, Iranian Journal of Psychiatry (2016)
2. Prevalence of Anxiety, Depression and Stress in Cabg Candidate Patients and Factors Affecting It at Farshchian Cardiovascular Hospital in Hamadan, Iranian Journal of Health Education and Health Promotion (2021)
3. Introducing the Tehran Heart Center's Premature Coronary Atherosclerosis Cohort: Thc-Pac Study, Journal of Tehran University Heart Center (2015)
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