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Advances in Perinatal Stem Cells Research: A Precious Cell Source for Clinical Applications Publisher Pubmed



Abbaspanah B1 ; Momeni M2 ; Ebrahimi M2, 3 ; Mousavi SH4
Authors
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Authors Affiliations
  1. 1. Royan Stem Cell Technology Company, Cord Blood Bank, Tehran, Iran
  2. 2. Department of Regenerative Biomedicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
  3. 3. Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
  4. 4. Department of Hematology, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran

Source: Regenerative Medicine Published:2018


Abstract

Perinatal tissues possess numerous types of stem (stromal) cells, which are considered effective candidates for cell therapy. These tissues possess common characteristics of both embryonic and adult stem cells, and cell therapists have begun to use perinatal stem cells to treat several diseases. Despite their benefits, these cells are considered biological waste and usually discarded after delivery. This review highlights the characteristics and potential clinical applications in regenerative medicine of perinatal stem cell sources - cord blood hematopoietic stem cells, umbilical cord mesenchymal stem cells, amniotic membrane stem cells, amniotic fluid stem cells, amniotic epithelial cells and chorionic mesenchymal stem cells. © 2018 Future Medicine Ltd.
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