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Ecological Study of Ambient Air Pollution Exposure and Mortality of Cardiovascular Diseases in Elderly Publisher Pubmed



Dehghani S1 ; Vali M2 ; Jafarian A3 ; Oskoei V1 ; Maleki Z2 ; Hoseini M4
Authors
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Authors Affiliations
  1. 1. Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran
  3. 3. Department of Environmental Health Engineering, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran
  4. 4. Department of Environmental Health Engineering, School of Public Health, Research Center for Health Sciences, Institute of Health, Shiraz University of Medical Sciences, Razi Blvd, Kuye-Zahra Ave, Shiraz, 1417653861, Iran

Source: Scientific Reports Published:2022


Abstract

As an independent risk factor, ambient air pollution can assume a considerable part in mortality and worsening of cardiovascular disease. We sought to investigate the association between long-term exposure to ambient air pollution and cardiovascular disease mortality and their risk factors in Iranian's elderly population. This inquiry was conducted ecologically utilizing recorded data on cardiovascular disease mortality from 1990 to 2019 for males and females aged 50 years or more from the Global Burden of Disease dataset. Data was interned into Joinpoint software 4.9.0.0 to present Annual Percent Change (APC), Average Annual Percent Change (AAPC), and its confidence intervals. The relationship between recorded data on ambient air pollution and cardiovascular disease' mortality, the prevalence of high systolic blood pressure, high LDL cholesterol levels, high body mass index, and diabetes mellitus type2 was investigated using the Spearman correlation test in R 3.5.0 software. Our finding demonstrated that cardiovascular diseases in elderly males and females in Iran had a general decreasing trend (AAPC = −0.77% and −0.65%, respectively). The results showed a positive correlation between exposure to ambient ozone pollution (p ≤ 0.001, r = 0.94) ambient particulate and air pollution (p < 0.001, r = 0.99) and mortality of cardiovascular disease. Also, ambient air pollution was positively correlated with high systolic blood pressure (p < 0.001, r = 0.98), high LDL cholesterol levels (p < 0.001, r = 0.97), high body mass index (p < 0.001, r = 0.91), diabetes mellitus type2 (p < 0.001, r = 0.77). Evidence from this study indicated that ambient air pollution, directly and indirectly, affects cardiovascular disease mortality in two ways by increasing the prevalence of some traditional cardiovascular disease risk factors. Evidence-based clinical and public health methodologies are necessary to decrease the burden of death and disability associated with cardiovascular disease. © 2022, The Author(s).
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