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Heart Murmurs Detected During Newborn Examination: A Case Report Highlighting the Need for Caution



Sheykhian T1 ; Amiri A1 ; Rezaeikalantari K2 ; Ghorbansabagh V1
Authors
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Authors Affiliations
  1. 1. Maternal, Fetal and Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran

Source: Iranian Heart Journal Published:2025

Abstract

In this case report, we examine a 2-day-old infant referred for evaluation due to the detection of a heart murmur. Coronary artery fistula, an anomalous connection between coronary arteries and a cardiac chamber or vascular structure bypassing the typical capillary network, is the focus of our discussion. The newborn displayed no symptoms, and all other physical assessments appeared normal. Transthoracic echocardiography uncovered an enlargement of the coronary arteries, notably the proximal right coronary artery. Furthermore, a color Doppler scan indicated turbulent flow at the terminal portion of the ventricular septum, revealing a fistula linking the right coronary artery to the right ventricle. Throughout a 1-year follow-up period, the fistula spontaneously closed, resulting in the resolution of the heart murmur. Remarkably, the diameters of the coronary arteries reverted to the standard range. It is noteworthy that while surgical or interventional methods are sometimes used to treat these patients, spontaneous closure may occur in asymptomatic cases with close monitoring over time. © 2025, Iranian Heart Association. All rights reserved.