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Dosimetric Evaluation of Gafchromic Ebt2 Film for Breast Intraoperative Electron Radiotherapy Verification Publisher Pubmed



Baghani HR1 ; Aghamiri SMR1 ; Mahdavi SR2 ; Robatjazi M3 ; Zadeh AR4 ; Akbari ME5 ; Mirzaei HR5 ; Nafissi N5 ; Samsami M5
Authors
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Authors Affiliations
  1. 1. Department of Radiation Medicine, Shahid Beheshti University, Daneshjoo St, Velenjak, Tehran, 1983963113, Iran
  2. 2. Department of Medical Physics, Iran University of Medical Science, Hemmat Exp.Way, Tehran, 14496141525, Iran
  3. 3. Department of Medical Physics, Tehran University of Medical Science, Poursina St, Tehran, 1417614411, Iran
  4. 4. Department of Medical Radiation, Islamic Azad University, Science and Research Branch, Hesark Blvd, Tehran, 1477893855, Iran
  5. 5. Cancer Research Center, Shahid Beheshti University of Medical Science, Shahrdari St, Tehran, 1985717443, Iran

Source: Physica Medica Published:2015


Abstract

Purpose: Quality assurance (QA) is one of the most important issues that should be addressed for intraoperative electron radiotherapy (IOERT), which is not benefiting from image-based treatment planning system. The aim of this study is to evaluate the dosimetric characteristics of Gafchromic EBT2 film for breast IOERT QA procedure. Methods: Due to the fact that some dedicated accelerators are being used for IOERT, dependence of the film response to energy, field size, dose rate and incidence angle of electron beam from the LIAC IOERT accelerator was studied. Then, film response curve to breast IOERT doses was obtained and its accuracy was evaluated and justified through comparison to the results of ionometric dosimetry. Results: The results of this study indicated that there are no significant differences between the film responses at different energies of 6, 8, 10 and 12MeV (P-value=0.99). Similarly, no field size dependency was found when evaluating the response of the film to different field sizes ranging from 4 to 10cm (P-value=0.94). Film response was found to be independent of the dose rate of intraoperative electron beam (P-value=0.12). Film response variations with changing the beam incidence angle were not significant (P-value>0.8). Calibration curve at the dose range of 8-24Gy had an acceptable accuracy. The difference between the results of film dosimetry and ionometric dosimetry was around 5% which was in agreement with the results of dose uncertainty estimation. Conclusion: The EBT2 film was found to be a potentially appropriate tool for breast IOERT verification. © 2014 Associazione Italiana di Fisica Medica.