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A Novel Phantom Design for Brachytherapy Quality Assurance Publisher



Gholami S1 ; Mirzaei HR2 ; Jabbary Arfaee A2 ; Jaberi R3 ; Nedaie HA1, 3 ; Rabi Mahdavi S4 ; Rajab Bolookat E2 ; Meigooni AS5
Authors
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Authors Affiliations
  1. 1. Department of Medical Physics and Biomedical Engineering, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Radiation Oncology Department, Shohada e Tajrish Hospital, Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Radiation Oncology Department, Cancer institute, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Medical Physics, Iran University of Medical Sciences, Tehran, Iran
  5. 5. Comprehensive Cancer Centers of Nevada, Las Vegas, NV, United States

Source: International Journal of Radiation Research Published:2016


Abstract

Background: One major challenge in brachytherapy is to verify the accuracy of dose distributions calculated by the treatment planning system. In this project, a new phantom design has been introduced for quality assurance of dose distributions in gynocological (GYN) brachytherapy implants using EBT GafChromic film. Materials and Methods: This phantom has been designed and fabricated from 90 slabs of 18×16×0.2 cm3 Perspex to accommodate a tandem and ovoids assembly, which is normally used for GYN brachytherapy treatment. In addition, this phantom design is allowing the use EBT GafChromic films for dosimetric verification of GYN implants with Cs-137 Selectron LDR system. With this assembly, GafChromic films were exposed using a plan designed to deliver 2.5 Gy dose to point A in Manchester system for tandem and ovoids configurations and to deliver 1.5 Gy of dose to 0.5 cm distance from the lateral surface of ovoids for using ovoid-pair. The measured dose distributions with GafChromic films were compared with the TPS isodose lines both numerically and spatially. For a quantitative analysis of the results, the measured doses values at several points of interest were evaluated with the treatment planning data and values obtained following the TG-43 dose calculation formalism. Results: The results of these investigations have indicated that the new phantom design enables us to measure differences of greater than ±6% for LDR brachytherapy GYN treatments. Conclusion: The new phantom design could be utilized for the QA procedure of the brachytherapy remote after loading systems to confirm the accuracy of dose distribution in GYN implants.
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