Stress-Induced Cardiomyopathy Following Kidney Transplant Publisher



V Eslami VAHID ; R Nazari ROOZBEH ; N Senobari NAHID ; A Alirezaei AMIRHESAM ; T Akbari TOUBA ; A Nasrollahizadeh AMIR ; P Ebrahimi POUYA ; R Ahmed RAHEEL ; Sq Khan Sohail Q ; F Shahid FARHAN
Source: JACC: Case Reports Published:2025

Abstract

Introduction: Takotsubo syndrome (TTS), commonly referred to as stress-induced cardiomyopathy, is a reversible type of nonischemic heart failure mimicking acute coronary syndrome. Case Presentation: A 55-year-old woman with end-stage renal disease experienced severe chest pain, dyspnea, and diaphoresis a few hours after undergoing a kidney transplant. Initial evaluations revealed ST-T wave changes alongside elevated troponin I levels. Echocardiography revealed a reduced left ventricular ejection fraction (LVEF) of 25% to 30% and apical wall motion abnormalities. Hence, coronary angiography was performed, which showed no significant coronary stenosis, a finding supporting a diagnosis of TTS. A follow-up transthoracic echocardiogram demonstrated a normalized LVEF 4 weeks later, thus confirming the provisional diagnosis. Discussion: This case highlights the necessity for clinicians to be vigilant for TTS in patients with acute cardiac conditions, specifically in patients undergoing significant physiological stress, such as post-surgery or following norepinephrine administration. © 2025 Elsevier B.V., All rights reserved.