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Optimal Cut-Off Value of Waist Circumference-To-Height Ratio to Predict Central Obesity in Children and Adolescents: A Systematic Review and Meta-Analysis of Diagnostic Studies Publisher



Eslami M1 ; Pourghazi F1 ; Khazdouz M2 ; Tian J3 ; Pourrostami K4 ; Esmaeiliabdar Z5 ; Ejtahed HS6 ; Qorbani M7, 8
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Authors Affiliations
  1. 1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Growth and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia
  4. 4. Social Determinants of Health Research Center, Alborz University of Medical Sciences, Karaj, Iran
  5. 5. Dietary Supplements and Probiotic Research Center, Alborz University of Medical Sciences, Karaj, Iran
  6. 6. Obesity and Eating Habits Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran
  8. 8. Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Frontiers in Nutrition Published:2023


Abstract

Introduction: Waist circumference-to-height ratio (WHtR) is a simple anthropometric index with good screening power and fast interpretation for early detection of childhood abdominal obesity. This systematic review and meta-analysis aims to determine the best cut-off value of WHtR to use in clinical setting. Methods: Comprehensive searches were conducted in PubMed, Scopus, and Web of Science by the end of March 2021. Observational studies investigated the best WHtR cut-off to detect abdominal obesity in children and adolescents were included. Thirteen articles (n = 180,119) were included in this systematic review and eight documents were included in the meta-analysis. Results: The overall optimal cut-off was 0.49 with pooled sensitivity, specificity and diagnostic odds ratio (DOR) of 0.93 (95% confidence interval (CI): 0.93–0.96), 0.88 (95% CI: 0.85–0.91) and 102.6 (95% CI: 50.7–207.5), respectively. The optimal WHtR cut-off to predict abdominal obesity in girls and boys were both 0.49. Discussion: The current study shows that we could use this cut-off as a simple index for predicting abdominal obesity in children and adolescents without the need for any charts in practice. Copyright © 2023 Eslami, Pourghazi, Khazdouz, Tian, Pourrostami, Esmaeili-Abdar, Ejtahed and Qorbani.
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