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Skewed Slash Censored Quantile Regression Publisher



Tatari M1 ; Zeraati H1 ; Yaseri M1 ; Kasaeian A2, 3, 4 ; Yazdani A5, 6 ; Mousavi SA7 ; Galarza CE8
Authors
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Authors Affiliations
  1. 1. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Digestive Oncology Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Clinical Research Development Unit, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Biostatistics and Epidemiology, Faculty of Health, Kashan University of Medical Sciences, Kashan, Iran
  6. 6. Autoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran
  7. 7. Hematology, Oncology and Stem Cell Transplantation Research Center, Research Institute for Oncology, Hematology and Cell Therapy, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Departamento de Matematicas, Escuela Superior Politecnica del Litoral, Guayaquil, 090112, Ecuador

Source: Sankhya B Published:2025


Abstract

In survival studies, the response variable is the time to desired event, which usually has skewness and censoring. For this reason, its mean modeling does not provide a complete picture of the density function. The quantile regression model investigates the effect of covariates in different percentiles by modeling duration time. The skewed slash distribution, having an addition parameter (υ), can change the tail width of the density function by changing its value, and is a more flexible distribution than other asymmetric distributions. We considered the skewed slash quantile regression model for survival data that interpret the effect of covariates on time-to-event. Likelihood-based approach and Nelder-Mead algorithm were used to fit the model. An application to data from AML patients receiving allo-HCT was presented to illustrate the theory and method developed in this paper. The Skewed slash distribution, by matching skewed data sets with heavy tails (Setting with the ν parameter), is useful for analyzing skewed and heavy tail data sets. © Indian Statistical Institute 2025.