Toxicity, Metabolism, and Mitigation Strategies of Acrylamide: A Comprehensive Review

Toxicity, Metabolism, and Mitigation Strategies of Acrylamide: A Comprehensive Review Publisher Pubmed

Peivastehroudsari L¹ ; Karami M² ; Barzegarbafrouei R³ ; Samiee S¹ ; Karami H² ; Tajdaroranj B¹ ; Mahdavi V⁴ ; Alizadeh AM^{5, 6} ; Sadighara P² ; Oliveri Conti G⁷ ; Mousavi Khaneghah A⁸

Show Affiliations

1. Food and Drug Administration, Iran Ministry of Health and Medical Education, Tehran, Iran
2. Department of Environmental Health, Food Safety Division, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Food Safety and Hygiene, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
4. Iranian Research Institute of Plant Protection, Agricultural Research, Education and Extension Organization (AREEO), Tehran, Iran
5. Social Determinants of Health Research Center, Zanjan University of Medical Sciences, Zanjan, Iran
6. Department of Food Safety and Hygiene, School of Public Health, Zanjan University of Medical Sciences, Zanjan, Iran
7. Department of Medical, Surgical and Advanced Technologies â€œG.F. Ingrassia, â€� Hygiene and Public Health, University of Catania, Catania, Italy
8. Department of Fruit and Vegetable Product Technology, Prof. Waclaw Dabrowski Institute of Agricultural and Food Biotechnology, State Research Institute, Warsaw, Poland

Source: International Journal of Environmental Health Research Published:2024

Abstract

Acrylamide, a food-borne chemical toxicant, has raised global concern in recent decades. It mainly originated from reducing sugar and free amino acid interactions in the carbohydrate-rich foodstuffs heated at high temperatures. Due to the neurotoxicity and carcinogenicity of AA, the mechanism of formation, toxic effects on health, and mitigation strategies, including conventional approaches and innovative technologies, have been of great interest since its discovery in food. Potato products (especially French fries and crisps), coffee, and cereals(bread and biscuit) are renowned contributors to AA’s daily intake. The best preventive methods discussed in the literature include time/temperature optimization, blanching, enzymatic treatment, yeast treatment, additives, pulsed electric fields, ultrasound, vacuum roasting, air frying, and irradiation, exhibiting a high efficacy in AA elimination in food products. © 2022 Informa UK Limited, trading as Taylor & Francis Group.

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Style	Citing Format
MLA	Peivastehroudsari L, et al.. "Toxicity, Metabolism, and Mitigation Strategies of Acrylamide: A Comprehensive Review." International Journal of Environmental Health Research, vol. 34, no. 1, 2024, pp. 1-29.
APA	Peivastehroudsari L, Karami M, Barzegarbafrouei R, Samiee S, Karami H, Tajdaroranj B, Mahdavi V, Alizadeh AM, Sadighara P, Oliveri Conti G, Mousavi Khaneghah A (2024). Toxicity, Metabolism, and Mitigation Strategies of Acrylamide: A Comprehensive Review. International Journal of Environmental Health Research, 34(1), 1-29.
Chicago	Peivastehroudsari L, Karami M, Barzegarbafrouei R, Samiee S, Karami H, Tajdaroranj B, Mahdavi V, et al.. "Toxicity, Metabolism, and Mitigation Strategies of Acrylamide: A Comprehensive Review." International Journal of Environmental Health Research 34, no. 1 (2024): 1-29.
Harvard	Peivastehroudsari L et al. (2024) 'Toxicity, Metabolism, and Mitigation Strategies of Acrylamide: A Comprehensive Review', International Journal of Environmental Health Research, 34(1), pp. 1-29.
Vancouver	Peivastehroudsari L, Karami M, Barzegarbafrouei R, Samiee S, Karami H, Tajdaroranj B, et al.. Toxicity, Metabolism, and Mitigation Strategies of Acrylamide: A Comprehensive Review. International Journal of Environmental Health Research. 2024;34(1):1-29.
BibTex	@article{ author = {Peivastehroudsari L and Karami M and Barzegarbafrouei R and Samiee S and Karami H and Tajdaroranj B and Mahdavi V and Alizadeh AM and Sadighara P and Oliveri Conti G and Mousavi Khaneghah A}, title = {Toxicity, Metabolism, and Mitigation Strategies of Acrylamide: A Comprehensive Review}, journal = {International Journal of Environmental Health Research}, volume = {34}, number = {1}, pages = {1-29}, year = {2024} }
RIS	TY - JOUR AU - Peivastehroudsari L AU - Karami M AU - Barzegarbafrouei R AU - Samiee S AU - Karami H AU - Tajdaroranj B AU - Mahdavi V AU - Alizadeh AM AU - Sadighara P AU - Oliveri Conti G AU - Mousavi Khaneghah A TI - Toxicity, Metabolism, and Mitigation Strategies of Acrylamide: A Comprehensive Review JO - International Journal of Environmental Health Research VL - 34 IS - 1 SP - 1 EP - 29 PY - 2024 ER -

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