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Pharmaceutical Implants: Classification, Limitations and Therapeutic Applications Publisher Pubmed



Mohtashami Z1 ; Esmaili Z1 ; Vakilinezhad MA1 ; Seyedjafari E2 ; Akbari Javar H1
Authors
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Authors Affiliations
  1. 1. Pharmaceutics Department, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Biotechnology, Tehran University, Tehran, Iran

Source: Pharmaceutical Development and Technology Published:2020


Abstract

Controlled/sustained delivery systems have been developed rapidly which show the ability to overcome the obstacles of traditional delivery systems. Daily development of biomedical and biomaterial sciences has brought more attention to the implantable delivery systems. As a result, these systems have found their position in the medical field since they were introduced. The advances in the polymeric science along with the other fields, make the production of a wide variety of implantable systems, possible. The influence of these systems in medical field could not be denied Here', the pharmaceutical applications which have been mostly focused on, are discussed. Since these systems have proven to be beneficial, researchers are trying to adjust their defects to the desired properties. Doing so, the path that implantable delivery systems have crossed so far should be studied, and that’s the aim of this review. In the present report, the advantages of these systems in chemotherapeutic, contraceptive, neuropsychology, pain management, peptide delivery, ocular delivery, cardiovascular, orthopedic, and dental fields have been evaluated. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.
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