Normal-Appearing Endometrial Cells in Pap Tests of Women Aged Forty Years or Older and Cytohistological Correlates

Normal-Appearing Endometrial Cells in Pap Tests of Women Aged Forty Years or Older and Cytohistological Correlates Publisher Pubmed

Izadimood N¹ ; Sarmadi S¹ ; Sanii S² ; Sadidi H²

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1. Department of Pathology, General Women Hospital, Tehran University of Medical Sciences, Nejatollahi St, Karim Khan Zand Ave, Tehran, 1597856511, Iran
2. Research Center, General Women Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Acta Cytologica Published:2015

Abstract

Objective: The Bethesda System 2001 for reporting cervical cytology recommends reporting benign-appearing, exfoliated endometrial cells in women aged 40 years or older. The objective of this study was to determine the significance of normal endometrial cells in conventional Papanicolaou (Pap) tests of women aged 40 years and older and to correlate this finding with histological follow-up. Study Design: Over a period of 5 years, all Pap tests showing endometrial cells in women aged ≥40 years were identified. Histological follow-up and outcome were evaluated. Results: Out of 17,275 Pap tests, 199 (1.15%) showed benign endometrial cells. Forty-seven of these 199 patients had subsequent tissue sampling by surgical procedures including endometrial curettage (n = 31), lower genital tract biopsy (n = 30) and hysterectomy (n = 2). Overall, out of 47 cases, 3 (6.4%) had significant endometrial pathology including 2 simple hyperplasias without atypia and 1 complex hyperplasia with atypia. Conclusion: The incidence of clinically significant endometrial lesions associated with the presence of endometrial cells in Pap tests of women aged 40 years and older was very low. Considering this finding, women aged between 40 and 50 years with benign endometrial cells in a Pap test should undertake endometrial sampling only when additional clinical indicators are recognized. © 2015 S. Karger AG, Basel.

Style	Citing Format
MLA	Izadimood N, et al.. "Normal-Appearing Endometrial Cells in Pap Tests of Women Aged Forty Years or Older and Cytohistological Correlates." Acta Cytologica, vol. 59, no. 2, 2015, pp. 175-179.
APA	Izadimood N, Sarmadi S, Sanii S, Sadidi H (2015). Normal-Appearing Endometrial Cells in Pap Tests of Women Aged Forty Years or Older and Cytohistological Correlates. Acta Cytologica, 59(2), 175-179.
Chicago	Izadimood N, Sarmadi S, Sanii S, Sadidi H. "Normal-Appearing Endometrial Cells in Pap Tests of Women Aged Forty Years or Older and Cytohistological Correlates." Acta Cytologica 59, no. 2 (2015): 175-179.
Harvard	Izadimood N et al. (2015) 'Normal-Appearing Endometrial Cells in Pap Tests of Women Aged Forty Years or Older and Cytohistological Correlates', Acta Cytologica, 59(2), pp. 175-179.
Vancouver	Izadimood N, Sarmadi S, Sanii S, Sadidi H. Normal-Appearing Endometrial Cells in Pap Tests of Women Aged Forty Years or Older and Cytohistological Correlates. Acta Cytologica. 2015;59(2):175-179.
BibTex	@article{ author = {Izadimood N and Sarmadi S and Sanii S and Sadidi H}, title = {Normal-Appearing Endometrial Cells in Pap Tests of Women Aged Forty Years or Older and Cytohistological Correlates}, journal = {Acta Cytologica}, volume = {59}, number = {2}, pages = {175-179}, year = {2015} }
RIS	TY - JOUR AU - Izadimood N AU - Sarmadi S AU - Sanii S AU - Sadidi H TI - Normal-Appearing Endometrial Cells in Pap Tests of Women Aged Forty Years or Older and Cytohistological Correlates JO - Acta Cytologica VL - 59 IS - 2 SP - 175 EP - 179 PY - 2015 ER -

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