Global Estimate of Phenotypic and Genotypic Ganciclovir Resistance in Cytomegalovirus Infections Among Hiv and Organ Transplant Patients; a Systematic Review and Meta-Analysis

Global Estimate of Phenotypic and Genotypic Ganciclovir Resistance in Cytomegalovirus Infections Among Hiv and Organ Transplant Patients; a Systematic Review and Meta-Analysis Publisher Pubmed

Azimi T^{1, 2} ; Tavakolian S³ ; Goudarzi H³ ; Pourmand MR¹ ; Faghihloo E³

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1. Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
2. Students Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Microbial Pathogenesis Published:2020

Abstract

Human cytomegalovirus (CMV), an opportunistic pathogen belonging to Herpesviridae family, is considered as one of the major causes of morbidity and mortality among wide variety of patients, particularly in transplant recipients and HIV positive patients. As this virus can be resistant to treatment, frequency of CMV in patients who receive organ transplantation and people suffering from AIDS was studied between 1980 and 2019. Medline (via PubMed), Embase, Web of Science, and the Iranian Database were reviewed, and Comprehensive Meta-Analysis (V2.0, Biostat) software analyzed all data. Finally, we used Cochran's Q-statistic to encounter heterogeneity between different studies. Meta-analyses indicated, GCV resistance was 14.1% (95% CI 11.2–17.7); however, in patients suffering from AIDS and organ transplantation were 19.5% (95% CI 14.7–25.4) and 11.4% (95% CI 8.1–15.8), respectively. There were increasing rates in the prevalence of GCV resistance in CMV among transplant recipients, and HIV positive patients. Therefore, evaluation of these refractory infections is beneficial. © 2020 Elsevier Ltd

Style	Citing Format
MLA	Azimi T, et al.. "Global Estimate of Phenotypic and Genotypic Ganciclovir Resistance in Cytomegalovirus Infections Among Hiv and Organ Transplant Patients; a Systematic Review and Meta-Analysis." Microbial Pathogenesis, vol. 141, no. , 2020, pp. -.
APA	Azimi T, Tavakolian S, Goudarzi H, Pourmand MR, Faghihloo E (2020). Global Estimate of Phenotypic and Genotypic Ganciclovir Resistance in Cytomegalovirus Infections Among Hiv and Organ Transplant Patients; a Systematic Review and Meta-Analysis. Microbial Pathogenesis, 141(), -.
Chicago	Azimi T, Tavakolian S, Goudarzi H, Pourmand MR, Faghihloo E. "Global Estimate of Phenotypic and Genotypic Ganciclovir Resistance in Cytomegalovirus Infections Among Hiv and Organ Transplant Patients; a Systematic Review and Meta-Analysis." Microbial Pathogenesis 141, no. (2020): -.
Harvard	Azimi T et al. (2020) 'Global Estimate of Phenotypic and Genotypic Ganciclovir Resistance in Cytomegalovirus Infections Among Hiv and Organ Transplant Patients; a Systematic Review and Meta-Analysis', Microbial Pathogenesis, 141(), pp. -.
Vancouver	Azimi T, Tavakolian S, Goudarzi H, Pourmand MR, Faghihloo E. Global Estimate of Phenotypic and Genotypic Ganciclovir Resistance in Cytomegalovirus Infections Among Hiv and Organ Transplant Patients; a Systematic Review and Meta-Analysis. Microbial Pathogenesis. 2020;141():-.
BibTex	@article{ author = {Azimi T and Tavakolian S and Goudarzi H and Pourmand MR and Faghihloo E}, title = {Global Estimate of Phenotypic and Genotypic Ganciclovir Resistance in Cytomegalovirus Infections Among Hiv and Organ Transplant Patients; a Systematic Review and Meta-Analysis}, journal = {Microbial Pathogenesis}, volume = {141}, number = {}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Azimi T AU - Tavakolian S AU - Goudarzi H AU - Pourmand MR AU - Faghihloo E TI - Global Estimate of Phenotypic and Genotypic Ganciclovir Resistance in Cytomegalovirus Infections Among Hiv and Organ Transplant Patients; a Systematic Review and Meta-Analysis JO - Microbial Pathogenesis VL - 141 IS - SP - EP - PY - 2020 ER -

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