The Impact of a Dedicated Coronavirus Disease 2019 Primary Angioplasty Protocol on Time Components Related to St-Segment Elevation Myocardial Infarction Management in a 24/7 Primary Percutaneous Coronary Intervention–Capable Hospital Publisher Pubmed



Salarifar M¹ ; Ghavami M¹ ; Poorhosseini H¹ ; Masoudkabir F¹ ; Jenab Y¹ ; Amirzadegan A¹ ; Alidoosti M¹ ; Aghajani H¹ ; Bozorgi A¹ ; Hosseini K¹ ; Lotfitokaldany M¹ ; Mortazavi SH¹ ; Aein A² ; Ahmadian T¹ Show All Authors Show Affiliations
Source: Kardiologia Polska Published:2020

Abstract

Background Primary percutaneous coronary intervention (PPCI) as the treatment of choice for ST-segment elevation myocardial infarction (STEMI) should be rapidly performed. It is necessary to use preventive strategies during the coronavirus disease 2019 (COVID-19) outbreak, which is an ongoing global concern. However, critical times in STEMI management may be influenced by the implementation of infection control protocols. aims We aimed to investigate the impact of our dedicated COVID-19 PPCI protocol on time components related to STEMI care and catheterization laboratory personnel safety. A subendpoint analysis to compare patient outcomes at a median time of 70 days during the pandemic with those of patients treated in the preceding year was another objective of our study. methods Patients with STEMI who underwent PPCI were included in this study. Chest computed tomography (CT) and real-time reverse transcriptase–polymerase chain reaction (rRT-PCR) tests were performed in patients suspected of having COVID-19. A total of 178 patients admitted between February 29 and April 30, 2020 were compared with 146 patients admitted between March 1 and April 30, 2019. results Severe acute respiratory syndrome coronavirus 2 infection was confirmed by rRT-PCR in 7 cases. In 6 out of 7 patients, CT was indicative of COVID-19. There were no differences between the study groups regarding critical time intervals for reperfusion in STEMI. The 70-day mortality rate before and during the pandemic was 2.73% and 4.49%, respectively (P = 0.4). conclusions The implementation of the dedicated COVID-19 PPCI protocol in patients with STEMI allowed us to achieve similar target times for reperfusion, short-term clinical outcomes, and staff safety as in the prepandemic era. Copyright by the Author(s), 2020.