Investigating the Association Between Dietary Nutrient Intake and Vitamin D Serum Levels Publisher



Sharifan P^{1, 2, 3} ; Amiri Z^{1, 4} ; Moafian F^{1, 4} ; Mohamadibajgiran M¹ ; Saffar Soflaei S¹ ; Darroudi S¹ ; Babaei A⁵ ; Harimi M⁵ ; Doolabian H⁵ ; Yousefi M⁵ ; Shojasiahi M⁵ ; Yaghoobinezhad M⁵ ; Ghazizadeh H^{1, 3} ; Shabani N⁶ Show All Authors
Source: Nutrire Published:2023

Abstract

Purpose: Concerning the effect of vitamin D on many organs and the increasing global prevalence of vitamin D deficiency, it is of paramount importance to determine the contributing factors affecting its serum level. By using the data mining approach, we aimed to investigate the association between serum vitamin D levels and dietary intake of micro- and macronutrients. Methods: This cross-sectional study is a part of the survey of ultraviolet intake by a nutritional approach (SUVINA) study and was conducted on 289 healthy individuals aged 30 to 50 years old in Mashhad, Iran. The dietary intake of different micro- and macronutrients was derived from a validated 65-item food frequency questionnaire. XGBoost modeler software was used to define the features with the highest impact on vitamin D levels. Results: Based on the XGBoost model results, dietary carbohydrates (21.54%), total dietary protein (16.60%), poly-saturated fat (16.60%), lactose (15.61%), total daily nitrogen (15.01%), and total sugar (14.62%) were identified as the six most important factors affecting serum vitamin D levels. The prediction accuracy for vitamin D levels was 89%. Conclusions: Dietary carbohydrates are the first and most important dietary component in the prediction of vitamin D levels, and other factors, including total dietary protein, poly-saturated fat, lactose, total nitrogen, and total sugar, are ranked as the important features thereafter. © 2023, The Author(s), under exclusive licence to Springer Nature Switzerland AG.