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Global, Regional, and National Prevalence of Depression Among Cancer Patients: A Systematic Review and Meta-Analysis Publisher



Mejareh Z1 ; Abdollahi B1 ; Hoseinipalangi Z2 ; Jeze M1 ; Hosseinifard H3 ; Rafiei S4 ; Aghajani F2 ; Dehnad A5 ; Ardakani M1 ; Ahmadi S2 ; Anbarhassani H2 ; Asl M2 ; Kan F2 ; Aryankhesal A6 Show All Authors
Authors
  1. Mejareh Z1
  2. Abdollahi B1
  3. Hoseinipalangi Z2
  4. Jeze M1
  5. Hosseinifard H3
  6. Rafiei S4
  7. Aghajani F2
  8. Dehnad A5
  9. Ardakani M1
  10. Ahmadi S2
  11. Anbarhassani H2
  12. Asl M2
  13. Kan F2
  14. Aryankhesal A6
  15. Shabaninejad H7
  16. Aghalou S8
  17. Ghashghaee A4, 9
Show Affiliations
Authors Affiliations
  1. 1. Medical School, Student Research Committee, Iran University of Medical Sciences, Tehran, Iran
  2. 2. Nursing and Midwife School, Student Research Committee, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran
  3. 3. Research Center for Evidence Based Medicine (RCEBM), Tabriz University of Medical Sciences, Tabriz, Iran
  4. 4. Center for Educational Research in Medical Sciences, Director of e Learning Center, Iran University of Medical Sciences, Tehran, Iran
  5. 5. Social Determinants of Health Research Center, Qazvin University of Medical Sciences, Qazvin, Iran
  6. 6. Department of Health Services Management, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran
  7. 7. Faculty of Medical Science (FMS), Population Health Sciences Institutes (PHSI), Newcastle University, Newcastle, United Kingdom
  8. 8. Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical Science, Tehran, Iran
  9. 9. Health Management and Economics Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, Iran

Source: Indian Journal of Psychiatry Published:2021


Abstract

This systematic review and meta-analysis aimed to provide a summary of the existing evidence on the prevalence of depression among cancer patients worldwide to assist health policymakers in adopting appropriate measures to prevent and control depression in these patients. EMBASE, Google Scholar, Scopus, PubMed, and Web of Science databases were searched for original studies published in English from January 2000 to July 2019. The studies were screened on the basis of quality and relevance criteria. The statistical analyses were conducted in the R software. Out of 182,521 cancer patients examined in 183 studies, 49,280 (~27%) had depression (95% confidence interval [CI] = 24%-30%). The highest prevalence of depression was among patients with colorectal cancer with 32% (95% CI = 20%-47%). Among countries, Pakistan with 43% (95% CI = 26%-64%), and among continents, Africa with 36% (95% CI = 29%-43%) had the highest prevalence of reported depression in cancer patients. Adjusting for sample size, the prevalence of depression among female cancer patients, 31% (95% CI = 26%-36%), was higher than men, 26% (95% CI = 21%-31%). The prevalence of depression among cancer patients is increasing by an average of 0.6% per year. The findings show higher prevalence of depression among cancer patients in underdeveloped and developing countries compared to the developed nations and the global average. © 2021 Wolters Kluwer Medknow Publications. All rights reserved.
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