Identification and Quantification of Ciprofloxacin, Enrofloxacin and Difloxacin Residues in Milk Using Excitation-Emission Fluorescence and Second-Order Standard Addition Methods

Identification and Quantification of Ciprofloxacin, Enrofloxacin and Difloxacin Residues in Milk Using Excitation-Emission Fluorescence and Second-Order Standard Addition Methods Publisher

Vali Zade S¹ ; Neymeyr K^{2, 3} ; Sawall M² ; Khoshayand MR⁴ ; Abdollahi H⁵

Show Affiliations

1. Halal Research Center of IRI, Food and Drug Administration, Ministry of Health and Medical Education, Tehran, Iran
2. University of Rostock, Institute of Mathematics, UlmenstraÃŸe 69, Rostock, 18057, Germany
3. Leibniz-Institute for Catalysis, Albert-Einstein-StraÃŸe 29a, Rostock, 18059, Germany
4. Department of Drug and Food Control, Faculty of Pharmacy, Tehran University of Medical Sciences, Iran
5. Faculty of Chemistry, Institute for Advanced Studies in Basic Sciences, Zanjan, 45195-1159, Iran

Source: Chemometrics and Intelligent Laboratory Systems Published:2023

Abstract

In the presence of non-modeled components and analyte-matrix interaction in real samples, a combination of second-order multivariate calibration and standard addition is desired to achieve accurate results via second-order advantage. Enrofloxacin (ENR), Difloxacin (DIF), and Ciprofloxacin (CIP) are Fluoroquinolones widely considered antibiotic residues in milk. Excitation-emission fluorescence spectra of these antibiotics at pH = 9.1 provide second-order data for identifying and quantifying them in a mixture using second-order calibration modeling. Rank annihilation factor analysis (RAFA) and multivariate curve resolution-alternating least squares (MCR-ALS) with trilinearity constraints are applied to determine the CIP, ENR, and DIF residues in synthetic mixtures and milk using second-order excitation-emission fluorescence spectroscopy. In both methods, the trilinearity constraint guarantees a unique true solution to the spectral profiles of analytes. The combination of second-order standard addition and higher-order calibration modeling with RAFA and MCR-ALS supports the second-order advantage in milk analysis. © 2023

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Experts (# of related papers)

Mohammad Reza Khoshayand (1)

Mahmoud Ghazi Khansari (1)

Style	Citing Format
MLA	Vali Zade S, et al.. "Identification and Quantification of Ciprofloxacin, Enrofloxacin and Difloxacin Residues in Milk Using Excitation-Emission Fluorescence and Second-Order Standard Addition Methods." Chemometrics and Intelligent Laboratory Systems, vol. 242, no. , 2023, pp. -.
APA	Vali Zade S, Neymeyr K, Sawall M, Khoshayand MR, Abdollahi H (2023). Identification and Quantification of Ciprofloxacin, Enrofloxacin and Difloxacin Residues in Milk Using Excitation-Emission Fluorescence and Second-Order Standard Addition Methods. Chemometrics and Intelligent Laboratory Systems, 242(), -.
Chicago	Vali Zade S, Neymeyr K, Sawall M, Khoshayand MR, Abdollahi H. "Identification and Quantification of Ciprofloxacin, Enrofloxacin and Difloxacin Residues in Milk Using Excitation-Emission Fluorescence and Second-Order Standard Addition Methods." Chemometrics and Intelligent Laboratory Systems 242, no. (2023): -.
Harvard	Vali Zade S et al. (2023) 'Identification and Quantification of Ciprofloxacin, Enrofloxacin and Difloxacin Residues in Milk Using Excitation-Emission Fluorescence and Second-Order Standard Addition Methods', Chemometrics and Intelligent Laboratory Systems, 242(), pp. -.
Vancouver	Vali Zade S, Neymeyr K, Sawall M, Khoshayand MR, Abdollahi H. Identification and Quantification of Ciprofloxacin, Enrofloxacin and Difloxacin Residues in Milk Using Excitation-Emission Fluorescence and Second-Order Standard Addition Methods. Chemometrics and Intelligent Laboratory Systems. 2023;242():-.
BibTex	@article{ author = {Vali Zade S and Neymeyr K and Sawall M and Khoshayand MR and Abdollahi H}, title = {Identification and Quantification of Ciprofloxacin, Enrofloxacin and Difloxacin Residues in Milk Using Excitation-Emission Fluorescence and Second-Order Standard Addition Methods}, journal = {Chemometrics and Intelligent Laboratory Systems}, volume = {242}, number = {}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Vali Zade S AU - Neymeyr K AU - Sawall M AU - Khoshayand MR AU - Abdollahi H TI - Identification and Quantification of Ciprofloxacin, Enrofloxacin and Difloxacin Residues in Milk Using Excitation-Emission Fluorescence and Second-Order Standard Addition Methods JO - Chemometrics and Intelligent Laboratory Systems VL - 242 IS - SP - EP - PY - 2023 ER -

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