Probiotics With Ameliorating Effects on the Severity of Skin Inflammation in Psoriasis: Evidence From Experimental and Clinical Studies Publisher Pubmed



Atabati H¹ ; Esmaeili SA^{2, 3} ; Saburi E^{4, 5} ; Akhlaghi M⁶ ; Raoofi A⁷ ; Rezaei N^{8, 9, 10} ; Momtaziborojeni AA^{11, 12}
Source: Journal of Cellular Physiology Published:2020

Abstract

Experimental and clinical studies have confirmed safety and the medical benefits of probiotics as immunomodulatory medications. Recent advances have emphasized the critical effect of gastrointestinal bacteria in the pathology of inflammatory disorders, even, outside the gut. Probiotics have shown promising results for curing skin-influencing inflammatory disorders through modulating the immune response by manipulating the gut microbiome. Psoriasis is a complex inflammatory skin disease, which exhibits a microbiome distinct from the normal skin. In the present review, we considered the impact of gastrointestinal microbiota on the psoriasis pathogenesis, and through literature survey, attempted to explore probiotic species utilized for psoriasis treatment. © 2020 Wiley Periodicals, Inc.