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Asymptomatic Isolated Retroperitoneal Castleman’S Disease: A Case Report



Rajabiani A1 ; Abdollahi A2 ; Farahani Z3
Authors
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Authors Affiliations
  1. 1. Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Pathology, Imam Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Medical Sciences Published:2015

Abstract

Castleman’s disease, giant lymph node hyperplasia, is a kind of benign lymphoproliferative disease with gentle behavior. Its etiology and prevalence are unclear. This rare disease is usually found in mediastinal area asymptomatically and incidentally. It is also rare to see this tumor in the retroperitoneum. In this study, we have introduced a 34-yearold woman who referred just with occasional abdominal pain caused by compressive symptoms. Laboratory findings only reported microcytic anemia (MCH: 18.5, MCV: 63, Hemoglobin 10.2 g/dl). Chest and abdominal X-ray imaging showed no remarkable point. In abdominal ultrasonography, a solid and firm tumor with 12.2×5.3×6.6 cm was reported in patient’s retroperitoneum. Patient’s surgery was done and the tumor (covered by a fibrous thick capsule, with no bizarre appearance and bleeding) was completely removed. Pathologic examination indicated a Castleman’s tumor, type of unicentric and hyaline-vascular. This item had been one of the rare reported items of Castleman’s disease in the retroperitoneal space. © 2015 Shiraz University of Medical Sciences. All rights reserved.